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50878 Stag3

50878

Stag3

stromal antigen 3

protein-coding

Mus musculus

基因描述

Type Description
Definition stromal antigen 3

研究结论

Date Results Publications
2020-04-11 11:11:00 STAG3 deficiency has a major effect on DNA double-strand breaks number even in the absence of PRDM9, showing that its role is not restricted to canonical PRDM9-activated hotspots. 30853435
2017-11-18 10:42:00 Our genetic analysis demonstrates that cohesins containing STAG3 and REC8 are the main complex required for centromeric cohesion, and RAD21L cohesins are required for normal clustering of pericentromeric heterochromatin. Furthermore, the STAG3/REC8 and STAG3/RAD21L cohesins are the primary cohesins required for axis formation. 27172213
2015-02-14 13:26:00 our data suggests that STAG3 is required for structural changes of chromosomes that mediate chromosome pairing and synapsis, DNA repair and progression of meiosis. 24992337
2015-01-31 11:36:00 STAG3 is a strong candidate gene for male infertility 24608227
2014-08-09 11:07:00 STAG3 emerges as the key STAG cohesin involved in major functions of meiotic cohesin. 24797474

名称对应

Type IDs
Synonymous SA-2
Gene
UniProtKB-ID: STAG3_MOUSE
UniprotKB: O70576
UniParc: UPI00015DF1FA
EMBL: BC139011, AJ005678, BC139010
Ensembl: ENSMUSG00000036928
KO: mmu:50878
Nucleutide sequences
EMBL-CDS: CAA06669.1, AAI39011.1, AAI39012.1
Ensembl_TRS: ENSMUST00000162245, ENSMUST00000048028
Protein sequencees
Ensembl_PRO: ENSMUSP00000040945, ENSMUSP00000125523
RefSeq: XP_006504659.1, XP_011239250.1, XP_017176460.1, XP_006504663.1, XP_006504664.1, XP_017176461.1, NP_058660.2
Others
UniRef100: UniRef100_O70576
UniRef90: UniRef90_O70576
UniRef50: UniRef50_O70576
UniGene: Mm.285609
CCDS: CCDS39344.1

全选

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研究热度

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