| Type | Description |
|---|---|
| Definition | phosducin like |
| Date | Results | Publications |
|---|---|---|
| 2015-05-02 12:57:00 | PhLP1 binding stabilizes the Gbeta fold, disrupting interactions with CCT and releasing a PhLP1-Gbeta dimer for assembly with Ggamma. | 25675501 |
| 2014-02-08 12:25:00 | evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins. | 23888055 |
| 2010-01-21 00:00:00 | physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 and alternative splicing of the regulator | 12466282 |
| 2010-01-21 00:00:00 | cytosolic chaperonin complex-dependent mechanism exists for Gbeta5-RGS7 assembly that utilizes the co-chaperone activity of PhLP1 in a unique way | 19376773 |
| 2010-01-21 00:00:00 | PhLP phosphorylation permits the release of a PhLP x Gbeta intermediate from cytosolic chaperonin complex, allowing Ggamma to associate with Gbeta in this intermediate complex. | 16717095 |
| Type | IDs |
|---|---|
| Synonymous | PhLP |
| Gene |
UniProtKB-ID:
PHLP_HUMAN
UniprotKB:
Q13371
UniParc:
UPI0000131988,
UPI000387C1F5
EMBL:
AF083324,
AL117602,
U38236,
AF031463,
CH471090,
AL359512,
BC017227,
AK313429,
AF083325
Ensembl:
ENSG00000136940
KO:
hsa:5082
|
| Nucleutide sequences |
EMBL-CDS:
EAW87546.1,
AAC78848.1,
BAG36221.1,
AAC78849.1,
AAH17227.1,
CAB56011.1,
AAD01930.1,
AAA79724.1
Ensembl_TRS:
ENST00000259467
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000259467
RefSeq:
NP_005379.3
|
| Others |
UniRef100:
UniRef100_Q13371
UniRef90:
UniRef90_Q13371
UniRef50:
UniRef50_Q13371
UniGene:
Hs.271749,
Hs.620774
CCDS:
CCDS6845.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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