| Type | Description |
|---|---|
| Definition | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:13:00 | ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation. | 33639150 |
| 2021-04-03 13:31:00 | Knockout of ASAP1 induces autophagy in papillary thyroid carcinoma by inhibiting the mTOR signaling pathway. | 32307199 |
| 2021-02-20 13:32:00 | The BAR domain of the Arf GTPase-activating protein ASAP1 directly binds actin filaments. | 32444496 |
| 2020-11-28 13:12:00 | Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression. | 32235890 |
| 2020-06-13 12:20:00 | Mutations in the ARF N terminus that reduced binding also reduced GAP activity. We conclude that PIP2 regulates binding of ASAP1's PH domain to the ARF1 N terminus, which may partially regulate GAP activity. | 31591270 |
| Type | IDs |
|---|---|
| Synonymous | AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P |
| Gene |
UniProtKB-ID:
ASAP1_HUMAN,
A0A0A0MRE5_HUMAN
UniprotKB:
Q9ULH1,
A0A0A0MRE5
UniParc:
UPI0000351D6E,
UPI0000EE3232,
UPI0001637F41
EMBL:
AP005856,
CH471060,
AC009682,
AP006178,
AC131568,
AP006181,
AC103725,
AC139019,
AB033075,
BC137135,
BX537768
Ensembl:
ENSG00000153317
KO:
hsa:50807
|
| Nucleutide sequences |
EMBL-CDS:
AAI37136.1,
BAA86563.1,
CAD97831.1,
EAW92130.1,
EAW92131.1
Gene_ORFName:
hCG_2009092
Ensembl_TRS:
ENST00000518721,
ENST00000357668
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429900,
ENSP00000350297
RefSeq:
XP_006716628.1,
XP_011515354.1,
NP_060952.2,
XP_011515355.1,
XP_016868956.1,
XP_006716626.1,
NP_001234925.1,
NP_001349853.1,
XP_016868957.1,
NP_001349855.1,
NP_001349854.1,
XP_006716627.1
|
| Others |
UniRef100:
UniRef100_Q9ULH1,
UniRef100_A0A0A0MRE5
UniRef90:
UniRef90_Q9ULH1
UniRef50:
UniRef50_Q9QWY8
UniGene:
Hs.655552
CCDS:
CCDS6362.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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