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50789 Fbxl3

50789

Fbxl3

F-box and leucine-rich repeat protein 3

protein-coding

Mus musculus

基因描述

Type Description
Definition F-box and leucine-rich repeat protein 3

研究结论

Date Results Publications
2017-09-02 11:21:00 CRY2 and FBXL3 cooperatively degrade c-MYC preventing the development of cancer. 27840026
2014-01-25 11:10:00 Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex. 24085301
2013-05-25 11:02:00 By analyzing the Fbxl3 and Cryptochrome 1 double-mutant mice, we found that FBXL3 also regulates the amplitudes of E-box-driven gene expression. 23471982
2013-05-04 11:43:00 crystal structures of mammalian CRY2 in its apo, FAD-bound and FBXL3-SKP1-complexed forms 23503662
2013-04-27 12:09:00 FBXL21 plays a dual role: protecting CRY 1/2 proteins (CRY) from FBXL3 degradation in the nucleus and promoting CRY degradation within the cytoplasm. 23452855

名称对应

Type IDs
Synonymous AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm, Play68
Gene
UniProtKB-ID: FBXL3_MOUSE, Q5PRF6_MOUSE, Q8BNS3_MOUSE
UniprotKB: Q8C4V4, Q5PRF6, Q8BNS3
UniParc: UPI00000E9D51, UPI00000EB182, UPI00001D6A1F
EMBL: AK142007, AF176521, AE013600, AK080802, BC046330, AK080863, BC067203
Ensembl: ENSMUSG00000022124
KO: mmu:50789
Nucleutide sequences
EMBL-CDS: AAM92567.1, AAH46330.1, AAF09131.1, BAC38050.1, AAH67203.1, BAE24911.1, BAC38026.1
Ensembl_TRS: ENSMUST00000145693, ENSMUST00000022720, ENSMUST00000132004
Protein sequencees
Ensembl_PRO: ENSMUSP00000116044, ENSMUSP00000115843, ENSMUSP00000022720
RefSeq: NP_001347270.1, NP_056637.1, XP_006519306.1, NP_001347271.1, NP_001334530.1, XP_006519303.1, NP_001334529.1
Others
UniRef100: UniRef100_Q8C4V4, UniRef100_Q8BNS3
UniRef90: UniRef90_Q8C4V4, UniRef90_F7CKD7
UniRef50: UniRef50_Q8C4V4, UniRef50_F7CKD7
UniGene: Mm.214746
CCDS: CCDS27315.1, CCDS84159.1

全选

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