例如:"NBL1", "4681", "drought"
收藏
5078 PAX4

5078

PAX4

paired box 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition paired box 4

研究结论

Date Results Publications
2021-01-02 12:53:00 [Alternative Variants of Pax4 Human Comparative Transcriptional Activity]. 33009794
2018-09-08 11:21:00 genetic association studies in population in Republic of Korea: Data suggest that SNPs in PAX4 and GLP1R are associated with type 2 diabetes (T2D) in the population studied. In genome-wide associations, PAX4 Arg192His increased risk of T2D; GLP1R Arg131Gln decreased risk of T2D. (PAX4 = paired box 4 protein; GLP1R = glucagon-like peptide 1 receptor) 29941447
2018-08-04 10:11:00 The rs10229583 polymorphism near PAX4 is associated with gestational diabetes mellitus in Chinese women. 28730907
2017-09-02 12:23:00 Study identified the association of a PAX4 Asian-specific missense variant rs2233580 with type 2 diabetes in an exome-chip association analysis, supporting the involvement of PAX4 in the pathogenesis of type 2 diabetes. 27744525
2017-04-08 11:59:00 Viability of beta-cell was reduced under glucotoxic stress condition for the cells overexpressing either PAX4 R192H or PAX4 P321H or both. Thus these PAX4 polymorphisms may increase T2D risk by defective transcription regulation of target genes and/or decreased beta-cell survival in high glucose condition. 27334367

名称对应

Type IDs
Synonymous KPD, MODY9
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_001353039.1, NP_001353040.1
Others
UniGene: Hs.129706

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员