| Type | Description |
|---|---|
| Definition | polyprotein |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:07:00 | Nucleotide-dependent dynamics of the Dengue NS3 helicase. | 32371149 |
| 2020-02-29 11:07:00 | Infectivity of Dengue virus serotypes 1 and 2 is correlated with E-protein intrinsic dynamics but not to envelope conformations. | 30686666 |
| 2019-12-14 11:29:00 | Study of DENV-1 evolution in a Colombian population revealed a trend of higher nonsynonymous to synonymous diversity ratios among non-structural (NS) genes, and statistically significantly higher values among these ratios in the NS1 gene after DENV-1 strain replacement. Results suggest that the NS1 gene, rather than the E gene, may be a target of positive selection, although not mutually exclusive. | 30845200 |
| 2018-11-24 12:05:00 | The secreted, hexameric form of NS1 has a systemic toxic effect, inducing inflammatory cytokines and acting directly on endothelial cells to produce the hallmark of dengue disease, vascular leak.[review] | 29845527 |
| 2018-11-24 12:05:00 | The multifunctional NS3 and NS5 contain all the enzymatic activities required to synthesize the viral RNA genome.[review] | 29845531 |
| Type | IDs |
|---|---|
| Synonymous | polyprotein gene |
| Gene |
UniProtKB-ID:
POLG_DEN1W
UniprotKB:
P17763
UniParc:
UPI00000EFA6A
EMBL:
M23027,
U88535,
U88536,
D00503
KO:
vg:5075725
|
| Nucleutide sequences |
EMBL-CDS:
AAB70694.1,
AAB70695.1,
AAA42940.1,
BAA00395.1
|
| Protein sequencees |
RefSeq:
NP_059433.1
|
| Others |
UniRef100:
UniRef100_P17763
UniRef90:
UniRef90_P17763
UniRef50:
UniRef50_P17763
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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