| Type | Description |
|---|---|
| Definition | pro-apoptotic WT1 regulator |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:45:00 | PAR4 activation involves extracellular loop 3 and transmembrane residue Thr153. | 32575122 |
| 2020-10-31 13:19:00 | Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-beta/ Smad4 axis driving the cells towards lethal EMT. | 32439219 |
| 2020-10-24 14:10:00 | A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling. | 32649856 |
| 2020-10-24 14:07:00 | Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3. | 32135176 |
| 2020-05-16 11:18:00 | These findings have identified an in vivo antileukemic role for Par-4 through an NF-kappaB-dependent mechanism in TCL1-mediated CLL-like disease progression. | 30987970 |
| Type | IDs |
|---|---|
| Synonymous | PAR4, Par-4 |
| Gene |
UniProtKB-ID:
PAWR_HUMAN
UniprotKB:
Q96IZ0
UniParc:
UPI0000070738
EMBL:
CR536549,
U63809,
BC007018,
AY300794,
AF503628
Ensembl:
ENSG00000177425
KO:
hsa:5074
|
| Nucleutide sequences |
EMBL-CDS:
AAM27453.1,
AAH07018.1,
CAG38786.1,
AAC24947.1,
AAP43693.1
Ensembl_TRS:
ENST00000328827
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000328088
RefSeq:
XP_016874868.1,
NP_001341662.1,
XP_006719498.1,
NP_001341661.1,
NP_002574.2,
XP_016874867.1
|
| Others |
UniRef100:
UniRef100_Q96IZ0
UniRef90:
UniRef90_Q96IZ0
UniRef50:
UniRef50_Q96IZ0
UniGene:
Hs.643130
CCDS:
CCDS31863.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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