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50723 Icosl

50723

Icosl

icos ligand

protein-coding

Mus musculus

基因描述

Type Description
Definition icos ligand

研究结论

Date Results Publications
2020-02-29 12:35:00 work identified a potentially novel role for ICOSL, which serves as an endogenous alphavbeta3-selective antagonist to maintain glomerular filtration. 30747722
2017-10-28 12:06:00 study confirms the importance of ICOSL shedding in ICOS/ICOSL function and expression and it identifies ADAM10 as the most important sheddase for controlling ICOSL levels 28814605
2017-08-12 11:40:00 results showed that monocyte-derived osteoclast (OC)-like cells (MDOCs) express B7h during their differentiation, and that B7h triggering reversibly inhibits OC differentiation and function both in vitro and in vivo 27798154
2017-08-05 12:46:00 study concludse that lymphopenia-driven autoimmunity and the development of Tfh17 cells in Rasgrp1-deficient mice occur independently of CD275(B7-H2) 27183569
2017-06-24 10:54:00 The expression of ICOSL in the cornea and the ICOS-mediated induction of Foxp3+ CD4+ regulatory T cells may contribute to successful corneal allograft survival. 28002569

名称对应

Type IDs
Synonymous AU044799, B7-H2, B7RP-1, B7h, BG071784, GI50, GL50, GL50-B, ICOS-L, Icoslg, LICOS, Ly115l, mKIAA0653
Gene
UniProtKB-ID: ICOSL_MOUSE, Q544C7_MOUSE
UniprotKB: Q9JHJ8, Q544C7
UniParc: UPI0000001A6B, UPI000002ABA7
EMBL: AF199027, AF216747, AX100593, BC029227, AK041421, AX100591, AF394451
Ensembl: ENSMUSG00000000732
KO: mmu:50723
Nucleutide sequences
EMBL-CDS: AAF45149.1, AAK77544.1, CAC36464.1, CAC36463.1, AAF34738.1, AAH29227.1, BAC30938.1
Ensembl_TRS: ENSMUST00000105393
Protein sequencees
Ensembl_PRO: ENSMUSP00000101032
RefSeq: XP_036011782.1, NP_056605.1
Others
UniRef100: UniRef100_Q9JHJ8
UniRef90: UniRef90_Q9JHJ8
UniRef50: UniRef50_Q9JHJ8
UniGene: Mm.17819
CCDS: CCDS35956.1

全选

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