| Type | Description |
|---|---|
| Definition | elastase, neutrophil expressed |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Mice Deficient in the IL-1beta Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD. | 32002713 |
| 2021-02-06 13:58:00 | Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice. | 32633320 |
| 2020-12-26 13:11:00 | Inducible expression of a disease-associated ELANE mutation impairs granulocytic differentiation, without eliciting an unfolded protein response. | 32299910 |
| 2020-07-18 10:43:00 | ELANE deficiency, and by extension ELANE-dependent neutrophil extracellular traps, had no effect on systemic lupus erythematosus nephritis, dermatitis, anti-self response, or immune composition in the MRL.Faslpr mouse model of lupus. | 32243431 |
| 2020-06-13 10:33:00 | CIRP induces neutrophil reverse transendothelial migration in sepsis by increasing neutrophil elastase and decreasing junctional adhesion molecule-C | 30148763 |
| Type | IDs |
|---|---|
| Synonymous | Ela2, F430011M15Rik, NE |
| Gene |
UniProtKB-ID:
ELNE_MOUSE
UniprotKB:
Q3UP87
UniParc:
UPI00000262E6
EMBL:
BC145800,
U06076,
AK143710,
U04962
Ensembl:
ENSMUSG00000020125
KO:
mmu:50701
|
| Nucleutide sequences |
EMBL-CDS:
AAB60670.1,
AAI45801.1,
BAE25510.1
Ensembl_TRS:
ENSMUST00000046091
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038925
RefSeq:
NP_056594.2
|
| Others |
UniRef100:
UniRef100_Q3UP87
UniRef90:
UniRef90_Q3UP87
UniRef50:
UniRef50_Q3UP87
UniGene:
Mm.262194
CCDS:
CCDS23994.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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