| Type | Description |
|---|---|
| Definition | retinol dehydrogenase 8 |
| Date | Results | Publications |
|---|---|---|
| 2012-05-05 11:16:00 | Progression of retinal degeneration in Rdh8-deficient Abca4-deficient mice is affected by differential vulnerability of rods and cones to light. | 22220722 |
| 2011-03-12 11:33:00 | Our family- and population-based data both suggest that the RDH8 gene is unlikely to be associated with high myopia in Chinese | 21043051 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 21043051 |
| 2010-01-21 00:00:00 | prRDH is an enzyme that catalyzes reduction of all-trans-retinal in the rod outer segment, most noticeably at higher light intensities and prolonged illumination, but is not an essential enzyme of the retinoid cycle | 15755727 |
| Type | IDs |
|---|---|
| Synonymous | PRRDH, SDR28C2 |
| Gene |
UniProtKB-ID:
RDH8_HUMAN,
K7ELF7_HUMAN
UniprotKB:
Q9NYR8,
K7ELF7
UniParc:
UPI0000072C8A,
UPI000059D661
EMBL:
AK024022,
AF229845,
AC008742
Ensembl:
ENSG00000080511
KO:
hsa:50700
|
| Nucleutide sequences |
EMBL-CDS:
AAF63160.1,
BAB14782.1
Ensembl_TRS:
ENST00000591589,
ENST00000651512
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000466058,
ENSP00000498711
RefSeq:
NP_056540.3
|
| Others |
UniRef100:
UniRef100_Q9NYR8
UniRef90:
UniRef90_Q9NYR8
UniRef50:
UniRef50_Q9NYR8
UniGene:
Hs.675522
CCDS:
CCDS12223.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28700943 |
A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells. Cell Rep Timothy D Martin , Danielle R Cook , Mei Yuk Choi , Mamie Z Li , Kevin M Haigis , Stephen J Elledge |
2017-07-11 | - |
| 25231870 |
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature John Rb Perry , Felix Day , Cathy E Elks , Patrick Sulem , Deborah J Thompson , Teresa Ferreira , Chunyan He , Daniel I Chasman , Tõnu Esko , Gudmar Thorleifsson , Eva Albrecht , Wei Q Ang , Tanguy Corre , Diana L Cousminer , Bjarke Feenstra , Nora Franceschini , Andrea Ganna , Andrew D Johnson , Sanela Kjellqvist , Kathryn L Lunetta , George McMahon , Ilja M Nolte , Lavinia Paternoster , Eleonora Porcu , Albert V Smith , Lisette Stolk , Alexander Teumer , Natalia TÅ¡ernikova , Emmi Tikkanen , Sheila Ulivi , Erin K Wagner , Najaf Amin , Laura J Bierut , Enda M Byrne , Jouke-Jan Hottenga , Daniel L Koller , Massimo Mangino , Tune H Pers , Laura M Yerges-Armstrong , Jing Hua Zhao , Irene L Andrulis , Hoda Anton-Culver , Femke Atsma , Stefania Bandinelli , Matthias W Beckmann , Javier Benitez , Carl Blomqvist , Stig E Bojesen , Manjeet K Bolla , Bernardo Bonanni , Hiltrud Brauch , Hermann Brenner , Julie E Buring , Jenny Chang-Claude , Stephen Chanock , Jinhui Chen , Georgia Chenevix-Trench , J Margriet Collée , Fergus J Couch , David Couper , Andrea D Coveillo , Angela Cox , Kamila Czene , Adamo Pio D'adamo , George Davey Smith , Immaculata De Vivo , Ellen W Demerath , Joe Dennis , Peter Devilee , Aida K Dieffenbach , Alison M Dunning , Gudny Eiriksdottir , Johan G Eriksson , Peter A Fasching , Luigi Ferrucci , Dieter Flesch-Janys , Henrik Flyger , Tatiana Foroud , Lude Franke , Melissa E Garcia , Montserrat GarcÃa-Closas , Frank Geller , Eco Ej de Geus , Graham G Giles , Daniel F Gudbjartsson , Vilmundur Gudnason , Pascal Guénel , Suiqun Guo , Per Hall , Ute Hamann , Robin Haring , Catharina A Hartman , Andrew C Heath , Albert Hofman , Maartje J Hooning , John L Hopper , Frank B Hu , David J Hunter , David Karasik , Douglas P Kiel , Julia A Knight , Veli-Matti Kosma , Zoltan Kutalik , Sandra Lai , Diether Lambrechts , Annika Lindblom , Reedik Mägi , Patrik K Magnusson , Arto Mannermaa , Nicholas G Martin , Gisli Masson , Patrick F McArdle , Wendy L McArdle , Mads Melbye , Kyriaki Michailidou , Evelin Mihailov , Lili Milani , Roger L Milne , Heli Nevanlinna , Patrick Neven , Ellen A Nohr , Albertine J Oldehinkel , Ben A Oostra , Aarno Palotie , Munro Peacock , Nancy L Pedersen , Paolo Peterlongo , Julian Peto , Paul Dp Pharoah , Dirkje S Postma , Anneli Pouta , Katri Pylkäs , Paolo Radice , Susan Ring , Fernando Rivadeneira , Antonietta Robino , Lynda M Rose , Anja Rudolph , Veikko Salomaa , Serena Sanna , David Schlessinger , Marjanka K Schmidt , Mellissa C Southey , Ulla Sovio , Meir J Stampfer , Doris Stöckl , Anna M Storniolo , Nicholas J Timpson , Jonathan Tyrer , Jenny A Visser , Peter Vollenweider , Henry Völzke , Gerard Waeber , Melanie Waldenberger , Henri Wallaschofski , Qin Wang , Gonneke Willemsen , Robert Winqvist , Bruce Hr Wolffenbuttel , Margaret J Wright , Australian Ovarian Cancer Study , GENICA Network , kConFab , LifeLines Cohort Study , InterAct Consortium , Early Growth Genetics (EGG) Consortium , Dorret I Boomsma , Michael J Econs , Kay-Tee Khaw , Ruth Jf Loos , Mark I McCarthy , Grant W Montgomery , John P Rice , Elizabeth A Streeten , Unnur Thorsteinsdottir , Cornelia M van Duijn , Behrooz Z Alizadeh , Sven Bergmann , Eric Boerwinkle , Heather A Boyd , Laura Crisponi , Paolo Gasparini , Christian Gieger , Tamara B Harris , Erik Ingelsson , Marjo-Riitta Järvelin , Peter Kraft , Debbie Lawlor , Andres Metspalu , Craig E Pennell , Paul M Ridker , Harold Snieder , Thorkild Ia Sørensen , Tim D Spector , David P Strachan , André G Uitterlinden , Nicholas J Wareham , Elisabeth Widen , Marek Zygmunt , Anna Murray , Douglas F Easton , Kari Stefansson , Joanne M Murabito , Ken K Ong |
2014-10-02 | - |
| 22220722 |
J. Neurochem. Kiichiro Okano , Akiko Maeda , Yu Chen , Vishal Chauhan , Johnny Tang , Grazyna Palczewska , Tsutomu Sakai , Hiroshi Tsuneoka , Krzysztof Palczewski , Tadao Maeda |
2012-04-01 | - |
| 21043051 |
J Zhejiang Univ Sci B Yan-shu Yu , Lin-ling Wang , Ye Shen , Maurice K H Yap , Shea-ping Yip , Wei Han |
2010-11-01 |
RDH8
|
| 19027726 |
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Chem Biol Interact Bengt Persson , Yvonne Kallberg , James E Bray , Elspeth Bruford , Stephen L Dellaporta , Angelo D Favia , Roser Gonzalez Duarte , Hans Jörnvall , Kathryn L Kavanagh , Natalia Kedishvili , Michael Kisiela , Edmund Maser , Rebekka Mindnich , Sandra Orchard , Trevor M Penning , Janet M Thornton , Jerzy Adamski , Udo Oppermann |
2009-03-16 | - |
| 17286855 |
Mapping of transcription start sites of human retina expressed genes. BMC Genomics Valeria Roni , Ronald Carpio , Bernd Wissinger |
2007-01-01 |
NXNL1,
WDR17,
CNGA3,
GRK7,
CRX,
RDH12,
EYA3,
AIPL1,
ABCA4,
SLC24A2,
FSCN2,
LRIT1,
PRPF31,
CLUL1,
GNAT1,
CRB2,
GUCY2D,
AOC2,
HPCA,
IMPG1,
KIFC3,
ILDR2,
RDH8,
IMPG2,
RDH11,
PDE6H,
CNGB3,
MPP4,
RBP3,
RCVRN,
RDH5,
PRPH2,
RGR,
RLBP1,
ELOVL5,
ROM1,
RP1,
RPGR,
RS1,
SAG,
ELOVL4,
TULP1,
DHRS3,
OPN4,
C14orf2
|
| 15755727 |
Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. J Biol Chem Akiko Maeda , Tadao Maeda , Yoshikazu Imanishi , Vladimir Kuksa , Andrei Alekseev , J Darin Bronson , Houbin Zhang , Li Zhu , Wenyu Sun , David A Saperstein , Fred Rieke , Wolfgang Baehr , Krzysztof Palczewski |
2005-05-13 | - |
| 15322982 |
Retinal dehydrogenase 12 (RDH12) mutations in leber congenital amaurosis. Am J Hum Genet Isabelle Perrault , Sylvain Hanein , Sylvie Gerber , Fabienne Barbet , Dominique Ducroq , Helene Dollfus , Christian Hamel , Jean-Louis Dufier , Arnold Munnich , Josseline Kaplan , Jean-Michel Rozet |
2004-10-01 | - |
| 15028754 |
J. Neurosci. Wenqin Luo , Nicholas Marsh-Armstrong , Amir Rattner , Jeremy Nathans |
2004-03-17 | - |
| 14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员