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50674 NEUROG3

50674

NEUROG3

neurogenin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition neurogenin 3

研究结论

Date Results Publications
2020-12-12 13:25:00 Reversible expansion of pancreatic islet progenitors derived from human induced pluripotent stem cells. 32065490
2020-06-13 12:25:00 PTEN and BMI1 help mediate NEUROGENIN-3-induced cell cycle arrest 31341016
2020-03-14 12:12:00 human organoid cells derived from the pancreatic tissue can be reprogrammed into the insulin-producing cells (IPCs) by the combination of in vitro transcribed modified mRNA encoding transcription factor neurogenin 3 and small molecules modulating the epigenetic state and signalling pathways. 31638558
2020-03-07 12:29:00 NEUROG3 pathogenic mutations affect protein stability, dimerization, and DNA binding. 31178402
2018-10-20 11:23:00 novel homozygous nonsense mutation (p.Q4*) as the genetic cause of neonatal diabetes mellitus and severe malabsorptive diarrhea in 2 cousins 28940958

名称对应

Type IDs
Synonymous Atoh5, Math4B, NGN-3, bHLHa7, ngn3
Gene
UniProtKB-ID: NGN3_HUMAN
UniprotKB: Q9Y4Z2
UniParc: UPI000013CB00
EMBL: AL450311, AF234829, BC117488, BC074939, BC126468, AK313952, CH471083, BC074938, AJ133776
Ensembl: ENSG00000122859
KO: hsa:50674
Nucleutide sequences
EMBL-CDS: CAB45384.1, AAK15022.1, BAG36669.1, AAH74938.1, EAW54328.1, AAI17489.1, AAI26469.1, AAH74939.1
Ensembl_TRS: ENST00000242462
Protein sequencees
Ensembl_PRO: ENSP00000242462
RefSeq: XP_016871769.1, NP_066279.2
Others
UniRef100: UniRef100_Q9Y4Z2
UniRef90: UniRef90_Q9Y4Z2
UniRef50: UniRef50_Q9Y4Z2
UniGene: Hs.532682
CCDS: CCDS31212.1

全选

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