| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:28:00 | Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease. | 32139661 |
| 2019-10-05 11:33:00 | The predicted expression of the ARHGEF3 gene in fibroblasts (effect, -0.48; P = 9.8 x 10-04) was associated with Major Depression. | 29998287 |
| 2018-03-17 12:09:00 | This is the first study describing the involvement of XPLN in the regulation of the axis, and these findings may help uncover regulatory mechanisms mediated by XPLN in idiopathic pulmonary fibrosis | 28315487 |
| 2017-12-09 10:20:00 | Our findings suggest that increased expression of ARHGEF3 plays a critical oncogenic role in nasopharyngeal carcinoma pathogenesis | 27028992 |
| 2017-09-23 11:19:00 | Data suggest that modulation of ARHGEF3 gene expression in humans with a promoter-localized SNP plays a role in human megakaryocytes and human platelet function-a finding resulting from the biological follow-up of human genetic studies. Arhgef3 KO mice partially recapitulate the human phenotype. | 28542600 |
| Type | IDs |
|---|---|
| Synonymous | GEF3, STA3, XPLN |
| Gene |
UniProtKB-ID:
ARHG3_HUMAN,
B7Z6B2_HUMAN,
E9PG37_HUMAN
UniprotKB:
Q9NR81,
B7Z6B2,
E9PG37
UniParc:
UPI0001914E3A,
UPI00001B3D98,
UPI0001B7948F,
UPI0001588789,
UPI0000031493,
UPI0001588788
EMBL:
AC097358,
AK300045,
AK291412,
AC099781,
AF433662,
AC099327,
AC099559,
BC098122,
BC098272,
BC099715,
AK024340,
AL136832,
AB209661,
BC068513,
CH471055,
BC104723,
BC054345,
AF249744
Ensembl:
ENSG00000163947
KO:
hsa:50650
|
| Nucleutide sequences |
EMBL-CDS:
AAH98272.2,
BAB14891.1,
AAI04724.2,
AAH98122.2,
BAD92898.1,
BAF84101.1,
AAF79954.1,
AAH99715.1,
CAB66766.1,
AAH68513.1,
AAP97313.1,
EAW65326.1,
AAH54345.2,
BAH13198.1
Ensembl_TRS:
ENST00000413728,
ENST00000338458,
ENST00000296315,
ENST00000496106
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000410922,
ENSP00000296315,
ENSP00000341071,
ENSP00000420420
RefSeq:
NP_001364340.1,
NP_001122087.1,
NP_062455.1,
NP_001364336.1,
NP_001364344.1,
XP_016861992.1,
NP_001122088.1,
XP_011532066.1,
XP_016861993.1,
NP_001364343.1,
NP_001364341.1,
NP_001364339.1,
NP_001364342.1,
NP_001364337.1,
NP_001276627.1,
XP_005265243.1,
XP_011532069.1,
NP_001364338.1
|
| Others |
UniRef100:
UniRef100_E9PG37,
UniRef100_B7Z6B2,
UniRef100_Q9NR81
UniRef90:
UniRef90_Q91X46-2,
UniRef90_Q9NR81
UniRef50:
UniRef50_Q9NR81
UniGene:
Hs.476402
CCDS:
CCDS46855.1,
CCDS46854.1,
CCDS2878.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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