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5063 PAK3

5063

PAK3

p21 (RAC1) activated kinase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition p21 (RAC1) activated kinase 3

研究结论

Date Results Publications
2021-03-27 14:41:00 PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration. 31843706
2021-01-16 15:53:00 Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease. 31410926
2020-11-21 13:16:00 Further delineation of the phenotype of PAK3-associated x-linked intellectual disability: Identification of a novel missense mutation and review of literature. 31678216
2020-09-19 16:30:00 Integration of hepatitis B virus DNA into p21-activated kinase 3 (PAK3) gene in HepG2.2.15 cells. 31897927
2020-04-18 12:18:00 PAK3 regulates the Akt-GSK3beta-beta-catenin signaling by acting as Ser(473)-Akt kinase in several pancreatic cancer cell lines, promoting cancer stem cell phenotypes. 31051214

名称对应

Type IDs
Synonymous ARA, MRX30, MRX47, OPHN3, PAK-3, PAK3beta, bPAK, beta-PAK
Gene
UniProtKB-ID: PAK3_HUMAN, B2RCU6_HUMAN
UniprotKB: O75914, B2RCU6
UniParc: UPI0000131224, UPI0000D61DBC, UPI00001B60C1, UPI0001750853, UPI0001718205
EMBL: AL356578, AB102269, AF068864, AB102299, AB102267, AM943850, CH471120, AB102297, AB102258, AB102300, AK315284, AB102659, AB102265, AB102290, AB102251, AB102266, AK290504, AB102262, AB102259, AB102255, AB102253, AB102292, AB102296, AL357774, AB102289, AB102252, AB102282, AB102260, AB102256, AB102254, AB102257, AB102263, AL117326, AB102291, AB102293, AB102270, AB102281, AF155651, AM943852, AB102286, AB102288, AL031117, AB102261, AB102295, AB102283, AB102294, AM943851, AB102268, AB102298, AB102284, AB102287, AB102264, AB102285
Ensembl: ENSG00000077264
KO: hsa:5063
Nucleutide sequences
EMBL-CDS: EAX02654.1, BAC80799.1, BAC80757.1, BAC81128.1, AAC36097.1, CAQ16018.1, BAC80768.1, BAC80760.1, BAC80786.1, BAC80756.1, BAC80754.1, BAC80789.1, BAC80787.1, CAQ16017.1, BAC80788.1, BAC80791.1, BAC80752.1, BAC80792.1, BAC80780.1, BAC80759.1, BAC80753.1, BAC80764.1, CAQ16016.1, BAC80795.1, BAF83193.1, BAC80793.1, BAC80767.1, BAC80781.1, BAC80751.1, BAC80798.1, BAC80782.1, BAC80755.1, AAF67008.1, BAC80785.1, BAC80766.1, BAC80761.1, BAC80783.1, BAC80796.1, BAC80797.1, BAC80794.1, BAC80750.1, BAC80784.1, BAC80769.1, BAC80758.1, BAC80763.1, BAC80765.1, BAC80762.1, BAC80790.1, BAG37693.1
Ensembl_TRS: ENST00000360648, ENST00000446737, ENST00000372007, ENST00000519681, ENST00000262836, ENST00000372010, ENST00000425146, ENST00000518291, ENST00000417227
Protein sequencees
Ensembl_PRO: ENSP00000428921, ENSP00000262836, ENSP00000401982, ENSP00000429113, ENSP00000410853, ENSP00000389172, ENSP00000361077, ENSP00000353864, ENSP00000361080
RefSeq: XP_005262189.1, XP_016885049.1, XP_011529271.1, NP_001121639.1, NP_001311261.1, XP_016885051.1, XP_016885047.1, NP_001121644.1, XP_011529273.1, NP_001311260.1, NP_001311257.1, NP_001311263.1, NP_001311259.1, NP_001311262.1, XP_006724717.1, NP_001121638.1, XP_016885046.1, NP_002569.1, XP_016885050.1, XP_011529270.1, NP_001121645.1, XP_016885048.1, XP_011529264.1, NP_001121640.1, XP_005262190.1, NP_001311256.1, NP_001311254.1, XP_006724718.1, NP_001311258.1, NP_001311255.1, XP_016885052.1, XP_011529269.1
Others
UniRef100: UniRef100_O75914, UniRef100_B2RCU6
UniRef90: UniRef90_O75914
UniRef50: UniRef50_Q13177
UniGene: Hs.656789
CCDS: CCDS48152.1, CCDS14554.1, CCDS48153.1, CCDS48151.1

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