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50619 DEF6

50619

DEF6

DEF6 guanine nucleotide exchange factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition DEF6 guanine nucleotide exchange factor

研究结论

Date Results Publications
2017-05-06 20:36:00 this study identifies Def6 as a novel inhibitor of osteoclastogenesis in physiological and inflammatory conditions 28314855
2017-02-18 11:48:00 DEF6 expression may serve as an independent prognostic factor, and interacted positively with p16 toward high tumor stage and shorter survival. 27488395
2013-03-23 11:50:00 IBP was expressed ectopically in someoral squamous cell carcinoma samples and correlated significantly with tumor size, differentiation, clinical stage and distant metastases 23088770
2012-11-24 11:01:00 DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies. 22829599
2010-09-15 22:06:00 Observational study of gene-disease association. (HuGE Navigator) 20546612

名称对应

Type IDs
Synonymous IBP, SLAT, SWAP70L
Gene
UniProtKB-ID: DEFI6_HUMAN
UniprotKB: Q9H4E7
UniParc: UPI000006E74E
EMBL: AJ276095, Z97832, AY241694
Ensembl: ENSG00000023892
KO: hsa:50619
Nucleutide sequences
EMBL-CDS: CAC08450.1, AAO91767.1
Ensembl_TRS: ENST00000316637
Protein sequencees
Ensembl_PRO: ENSP00000319831
RefSeq: NP_071330.3
Others
UniRef100: UniRef100_Q9H4E7
UniRef90: UniRef90_Q9H4E7
UniRef50: UniRef50_Q9H4E7
UniGene: Hs.15476
CCDS: CCDS4802.1

全选

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研究热度

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