| Type | Description |
|---|---|
| Definition | intersectin 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 11:47:00 | These findings provide the basis for further functional investigations of the ITSN/CR16 complex that may play an important role in actin remodeling and cellular invasion. | 28161632 |
| 2016-09-10 11:32:00 | ITSN2L interacts with RABEP1 and stimulates its degradation in regulation of endocytosis. | 26633357 |
| 2014-12-27 11:13:00 | The ITSN2 interacts with Eps8 and stimulates the degradation of Eps8 proteins. | 22449706 |
| 2014-03-08 10:57:00 | ITSN1 and ITSN2 bind similar proline-rich ligands but are differentially recognized by SH2 domain-containing proteins. | 23936226 |
| 2013-08-03 12:02:00 | The sequence and structural alignment of ITSN-2L C2 domain with other members of C2 domain protein family indicate its vital cellular roles in membrane trafficking, the generation of lipid-second messengers and activation of GTPases. Moreover, our data show the possible roles of ITSN-2L C2 domain in regulating the activity of Cdc42. | 23274495 |
| Type | IDs |
|---|---|
| Synonymous | PRO2015, SH3D1B, SH3P18, SWA, SWAP |
| Gene |
UniProtKB-ID:
ITSN2_HUMAN,
A6H8W8_HUMAN
UniprotKB:
Q9NZM3,
A6H8W8
UniParc:
UPI0000EE22A7,
UPI0001574E96,
UPI000013D414,
UPI000013D415,
UPI0001CE935B
EMBL:
BC146779,
AF248540,
AK000302,
AF182198,
AF001630,
AF182199,
U61167,
AB033082,
AK021545,
AC009228,
AC008073
Ensembl:
ENSG00000198399
KO:
hsa:50618
|
| Nucleutide sequences |
EMBL-CDS:
AAF59903.1,
BAA86570.1,
AAD00899.1,
BAB13841.1,
AAC50593.1,
AAF63600.1,
BAA91068.1,
AAF59904.1,
AAI46780.1
Ensembl_TRS:
ENST00000355123,
ENST00000361999,
ENST00000406921
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354561,
ENSP00000384499,
ENSP00000347244
RefSeq:
NP_671494.2,
NP_001335114.1,
NP_001335115.1,
XP_024308702.1,
NP_006268.2,
NP_062541.3,
XP_024308704.1,
XP_024308699.1,
NP_001335113.1,
XP_024308700.1,
NP_001335110.1,
XP_024308698.1,
XP_024308705.1,
XP_024308701.1,
NP_001335112.1,
XP_024308703.1,
NP_001335111.1
|
| Others |
UniRef100:
UniRef100_Q9NZM3,
UniRef100_A6H8W8
UniRef90:
UniRef90_Q9NZM3,
UniRef90_H2QHJ1
UniRef50:
UniRef50_Q9NZM3
UniGene:
Hs.432562
CCDS:
CCDS1710.2,
CCDS46230.1,
CCDS1711.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员