| Type | Description |
|---|---|
| Definition | interleukin 21 receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 15:20:00 | The IL21/IL21R axis reduced the growth and invasion of NSCLC cells via inhibiting Wnt/betacatenin signaling and PDL1 expression. The present results may provide a novel molecular target for NSCLC diagnosis and therapy. | 31573051 |
| 2019-12-14 11:19:00 | IL-21R rs2285452 AA genotype increases the risk of hepatitis B-related hepatocellular carcinoma in Chinese patients. | 30758075 |
| 2019-05-04 10:14:00 | in IL-21R (rs3093390C/T) gene polymorphism, allele frequency of T is statistically different in the hepatitis B virus spontaneous clearance group compared to chronic hepatitis B virus infection cases | 30639626 |
| 2019-03-16 11:04:00 | Results showed the upregulation of IL-21R in gastric cancer (GC) associated with tumor size and lymphatic metastasis and acted as an independent prognostic factor of a poor survival and recurrence in GC. IL-21R functioned as an oncogenic factor and alleviated the suppressive effects of miR-125a in GC cells. | 30387833 |
| 2018-11-17 11:33:00 | The number of IL-2-dependent FoxP3(+) regulatory T cells is increased in the peripheral blood of human patients with loss-of-function mutations in the IL-21 receptor (IL-21R). | 28303891 |
| Type | IDs |
|---|---|
| Synonymous | CD360, IMD56, NILR |
| Gene |
UniProtKB-ID:
IL21R_HUMAN
UniprotKB:
Q9HBE5
UniParc:
UPI0000043CF0
EMBL:
AK292663,
AY064474,
AF269133,
BC004348,
CH471145,
AY358826,
AF254067,
BC007946
Ensembl:
ENSG00000103522
KO:
hsa:50615
|
| Nucleutide sequences |
EMBL-CDS:
AAH04348.1,
AAQ89185.1,
EAW55747.1,
EAW55746.1,
AAH07946.2,
AAG29346.1,
BAF85352.1,
EAW55748.1,
AAG23419.1,
AAL39168.1
Gene_ORFName:
UNQ3121/PRO10273
Ensembl_TRS:
ENST00000337929,
ENST00000564089,
ENST00000395754
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379103,
ENSP00000338010,
ENSP00000456707
RefSeq:
XP_011544159.1,
XP_011544160.1,
NP_851564.1,
XP_016878746.1,
NP_068570.1,
NP_851565.4
|
| Others |
UniRef100:
UniRef100_Q9HBE5
UniRef90:
UniRef90_Q9HBE5
UniRef50:
UniRef50_Q9HBE5
UniGene:
Hs.210546
CCDS:
CCDS10630.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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