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506 ATP5F1B

506

ATP5F1B

ATP synthase F1 subunit beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATP synthase F1 subunit beta

研究结论

Date Results Publications
2019-11-30 12:25:00 Data show that ectopic plasma membrane ATP5B denotes a high metastasis-risk phenotype in breast and prostate cancer, and a vulnerability of cancer cells in vivo. Across multiple datasets, ATP5B expression was significantly increased in the tumors relative to normal tissue, and negatively correlated with metastasis-free and overall survival. 31006104
2019-10-19 10:14:00 results shed light on the role of host proteins in RV genome assembly and particle formation and identify ATP5B as a novel pro-RV RNA-binding protein, contributing to our understanding of how host ATP synthases may galvanize virus growth and pathogenesis. 30770472
2019-04-13 12:13:00 ATP5B reduction would be at least in part due to neuronal loss. 30539418
2018-11-03 11:15:00 The results revealed that ATP5B expression is associated with the process of keratinocyte differentiation which may be related to intracellular ATP synthesis. 28209970
2018-03-24 12:11:00 findings show the T163S mutation affects the catalytic activity with a decrease in Ca2+-dependent and an increase in Mg2+-dependent ATP hydrolysis and desensitizes the permeability transition pore to Ca2+, resulting in increased resistance to Ca2+-dependent mitochondrial depolarization and to cell death 28507163

名称对应

Type IDs
Synonymous ATP5B, ATPMB, ATPSB, HEL-S-271
Gene
UniProtKB-ID: ATPB_HUMAN, V9HW31_HUMAN
UniprotKB: P06576, V9HW31
UniParc: UPI000012644E
EMBL: X05606, BC016512, X03559, FJ224288, D00022, M27132, AK291085, M19483, CH471054, M19482
Ensembl: ENSG00000110955
KO: hsa:506
Nucleutide sequences
EMBL-CDS: CAA29095.1, AAA51809.1, AAA51808.1, EAW96952.1, BAA00016.1, BAF83774.1, CAA27246.1, AAH16512.1, ACI45980.1
Ensembl_TRS: ENST00000262030
Protein sequencees
Ensembl_PRO: ENSP00000262030
RefSeq: NP_001677.2
Others
UniRef100: UniRef100_P06576
UniRef90: UniRef90_P06576
UniRef50: UniRef50_P06576
UniGene: Hs.406510
CCDS: CCDS8924.1

全选

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