| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel subfamily J member 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 10:13:00 | Study is first to show direct cleavage of GIRK1 and GIRK2 subunits by caspase-3, with cleavage sites in GIRK1 (387ECLD390) and GIRK2 (349YEVD352) and suggests the possible role of caspase-3 mediated down-regulation of GIRK channel function and expression in hippocampal neuronal injury during prolonged epileptic seizures. | 28951616 |
| 2017-11-25 15:47:00 | Transient activation of mGluRs decreased the GIRK current evoked by GABAB and D2 receptors, although less efficaciously for D2. | 28009293 |
| 2017-05-13 20:28:00 | Study provides evidence that Kir3.1 is involved in the pathogenesis of sinus bradycardia since its ihibition with siRNA can reverse the sinus bradycardia. | 28205094 |
| 2016-06-11 10:46:00 | inwardly rectifying K+ channels coupled to 5-HT1A autoreceptors display pharmacological properties generally expected for neuronal GIRK channels, but different from GIRK1-GIRK2 heteromers | 26460748 |
| 2016-03-12 11:23:00 | Fourteen days after axotomy, GIRK1 and GIRK2 were down-regulated in DRG neurons at the mRNA and protein levels. | 26199148 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
KCNJ3_RAT
UniprotKB:
P63251
UniParc:
UPI0000022A06
EMBL:
U01071,
L25264,
U01141,
Y12259,
U09243
Ensembl:
ENSRNOG00000005369
KO:
rno:50599
|
| Nucleutide sequences |
EMBL-CDS:
AAC52127.1,
AAA18031.1,
AAC52125.1,
CAA72936.1,
AAA41226.1
Ensembl_TRS:
ENSRNOT00000007335
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007335
RefSeq:
NP_113798.1
|
| Others |
UniRef100:
UniRef100_P63250
UniRef90:
UniRef90_P48549
UniRef50:
UniRef50_P48549
UniGene:
Rn.9809
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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