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50563 Gja5

50563

Gja5

gap junction protein, alpha 5

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition gap junction protein, alpha 5

研究结论

Date Results Publications
2018-07-21 11:22:00 The A96S, G38D, and P88S Cx40 mutations slow conduction and increased the propensity for inducible AF. 28457700
2018-07-14 10:05:00 Lipopolysaccharide impairs permeability of pulmonary microvascular endothelial cells via Connexin40/protein kinase C/nfkappaB pathway. 28870649
2018-01-13 11:10:00 This study demonstrated the Cx40 was upregulated after traumatic brain injury in a linear correlated manner with increased oxidative stress. 28157110
2017-07-15 10:12:00 data are consistent with contributions of G2 and D3 residues to Cx40 channel pore structure, but not with postulated hydrophobic W4 intermolecular interactions; results indicate an absolute requirement for an amphipathic W3/4 residue; alternatively hypothesize that the connexin D2/3-W3/4 locus interacts with the highly conserved FIFR M1 motif to stabilize the NT domain within the pore 27304225
2016-07-30 11:45:00 Data show that the ratio of peripheral blood CD4(+)/CD8(+) T lymphocytes and the levels of connexin-40 (Cx40), interleukins IL-2, IL-4 and IL-6 are significantly elevated in SH rats. 26927369

名称对应

Type IDs
Synonymous Cx40
Gene
UniProtKB-ID: CXA5_RAT
UniprotKB: P28234
UniParc: UPI0000167950
EMBL: AF022136, M83092, AF021806, BC070935, M76535
Ensembl: ENSRNOG00000017484
KO: rno:50563
Nucleutide sequences
EMBL-CDS: AAA41194.1, AAA41000.1, AAC53503.1, AAC53502.1, AAH70935.1
Ensembl_TRS: ENSRNOT00000023488
Protein sequencees
Ensembl_PRO: ENSRNOP00000023488
RefSeq: NP_062153.1
Others
UniRef100: UniRef100_P28234
UniRef90: UniRef90_P28234
UniRef50: UniRef50_P36382
UniGene: Rn.88300

全选

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研究热度

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