| Type | Description |
|---|---|
| Definition | cytochrome P450, family 4, subfamily a, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 10:55:00 | These results indicated that AngII chronically increased the CYP4A isoform expression in the rat kidney. The AngII-induced CYP4A isoform expression was mediated by AT1-R. | 30227249 |
| 2018-01-27 11:13:00 | The CYP4A pathway plays a role in vascular dysfunction in SS rats and there appears to be a direct role of reduced NO availability due to salt-induced oxidant stress in upregulating CYP4A enzyme expression. | 27537772 |
| 2016-01-16 11:30:00 | rosuvastatin downregulates CYP4A1 in spontaneously hypertensive rats | 25636742 |
| 2015-05-02 12:54:00 | In CYP4A1 transgenic Dahl salt-sensitive rat formation of 20-HETE in the cerebral vasculature was elevated rescuing impaired myogenic response/autoregulation of cerebrovascular blood flow. | 25540098 |
| 2013-01-26 10:47:00 | Salt sensitive rats have an up-regulation of the CYP4A/20-HETE pathway resulting in elevated reactive oxygen species and reduced NO bioavailability causing vascular dysfunction. | 22938512 |
| Type | IDs |
|---|---|
| Synonymous | CYPIVA10, Cyp4a10, Cyp4a22 |
| Gene |
UniProtKB-ID:
CP4AA_RAT
UniprotKB:
P08516
UniParc:
UPI0000167F3D
EMBL:
X07259,
M57718,
BC089761,
M14972
Ensembl:
ENSRNOG00000009597
KO:
rno:50549
|
| Nucleutide sequences |
EMBL-CDS:
AAA41061.1,
AAA41038.1,
CAA30245.1,
AAH89761.1
Ensembl_TRS:
ENSRNOT00000012888
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000012888
RefSeq:
NP_787031.1,
XP_017449083.1,
XP_006238774.1
|
| Others |
UniRef100:
UniRef100_P08516
UniRef90:
UniRef90_P08516
UniRef50:
UniRef50_P08516
UniGene:
Rn.92401
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员