| Type | Description |
|---|---|
| Definition | ERO1-like (S. cerevisiae) |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | ERO1alpha promotes testosterone secretion in hCG-stimulated mouse Leydig cells via activation of the PI3K/AKT/mTOR signaling pathway. | 31990068 |
| 2017-07-08 10:26:00 | this study shows that the hypoxia-inducible ER-resident oxidase ERO1-alpha plays an important role in the hypoxia-induced augmentation of MHC class I-peptide complex expression | 27667124 |
| 2015-04-25 12:23:00 | Data (including data from knockout mice) suggest that up-regulation of expression of ERO1alpha (oxidoreductin-1-L-alpha) and CHOP (c/EBP-homologous protein) is involved in liver apoptosis/necrosis exhibited in acute liver failure. | 25387528 |
| 2015-04-25 11:33:00 | These results suggest that overexpression of ERO1-alpha in the tumor inhibits the T cell response by recruiting polymorphonuclear myeloid-derived suppressor cells | 25595776 |
| 2014-01-04 13:11:00 | ER stress induced by misfolded proinsulin was limited by increased expression of Ero1alpha, suggesting that enhancing the oxidative folding of proinsulin may be a viable therapeutic strategy in the treatment of type 2 diabetes. | 24022479 |
| Type | IDs |
|---|---|
| Synonymous | ERO1-L, Ero1a |
| Gene |
UniProtKB-ID:
ERO1A_MOUSE,
Q4FK57_MOUSE
UniprotKB:
Q8R180,
Q4FK57
UniParc:
UPI0000029CE0
EMBL:
BC025102,
CT010195,
AK009667,
AF144695,
AK142595
Ensembl:
ENSMUSG00000021831
KO:
mmu:50527
|
| Nucleutide sequences |
EMBL-CDS:
AAF20364.1,
BAB26428.1,
AAH25102.1,
CAJ18403.1,
BAE25121.1
Ensembl_TRS:
ENSMUST00000022378
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022378
RefSeq:
NP_056589.1
|
| Others |
UniRef100:
UniRef100_Q8R180
UniRef90:
UniRef90_Q8R180
UniRef50:
UniRef50_Q8R180
UniGene:
Mm.387108
CCDS:
CCDS36893.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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