| Type | Description |
|---|---|
| Definition | excision repair cross-complementing rodent repair deficiency, complementation group 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 14:26:00 | ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes and that persistent DNA damage triggers chromatin changes that affect gene expression programs associated with NER disorders. | 28368372 |
| 2015-03-28 12:41:00 | these results establish USP45 as a new regulator of XPF-ERCC1 crucial for efficient DNA repair | 25538220 |
| 2014-07-26 11:18:00 | SLX4 is a tumor suppressor, which activates XPF-ERCC1 nuclease specificity in DNA crosslink repair. | 24726326 |
| 2010-01-21 00:00:00 | These data support the conclusion that, as in yeast, ERCC1-XPF facilitates double-strand breaks repair via an end-joining mechanism that is Ku86 independent. | 18541667 |
| 2010-01-21 00:00:00 | mitomycin C triggered sister chromatid exchanges in wild-type cells but chromatid fusions in Ercc1(-/-) and Xpf mutant cells, indicating that in their absence, repair of double-strand breaks(DSBs)is prevented. | 15199134 |
| Type | IDs |
|---|---|
| Synonymous | AI606920, Xpf |
| Gene |
UniProtKB-ID:
XPF_MOUSE,
Q3UEU6_MOUSE
UniprotKB:
Q9QZD4,
Q3UEU6
UniParc:
UPI00005AC87D,
UPI00000E683A
EMBL:
AF189285,
BC026792,
AK149326,
AC004155
Ensembl:
ENSMUSG00000022545
KO:
mmu:50505
|
| Nucleutide sequences |
EMBL-CDS:
AAC03240.1,
AAF03157.1,
AAH26792.1,
BAE28815.1
Ensembl_TRS:
ENSMUST00000023206
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023206
RefSeq:
NP_056584.2
|
| Others |
UniRef100:
UniRef100_Q9QZD4,
UniRef100_Q3UEU6
UniRef90:
UniRef90_Q3UEU6,
UniRef90_Q9QZD4
UniRef50:
UniRef50_Q92889,
UniRef50_Q3UEU6
UniGene:
Mm.287837
CCDS:
CCDS37256.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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