| Type | Description |
|---|---|
| Definition | E2F transcription factor 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 13:52:00 | The results strongly suggest that TLX acts through E2F6 to regulate islet beta cell proliferation. | 30981507 |
| 2018-10-20 10:47:00 | E2F6 suppresses Mdm2 expression in cells harboring the SNP309G allele but not the SNP309T allele. | 28925402 |
| 2018-06-16 11:17:00 | By comparison in HeLa, Dox induced apoptosis through upregulation of endogenous E2F1 involving post-transcriptional mechanisms, while E2F6 was down regulated with induction of the Checkpoint kinase-1 and proteasome degradation. These data imply that E2F6 serves to modulate E2F activity and protect cells including cardiomyocytes from apoptosis and improve survival. | 28964969 |
| 2016-04-09 11:04:00 | These data reveal a novel interplay between the E2F pathway, and ERK/c-Src axis in fine tuning the pathological hypertrophic growth response. | 25944088 |
| 2014-04-05 13:44:00 | E2f6 was similarly bound to the proximal promoter regions both in embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) | 23880518 |
| Type | IDs |
|---|---|
| Synonymous | AI462434, E2F6a, E2F6b, EMA |
| Gene |
UniProtKB-ID:
E2F6_MOUSE,
Q8VHT4_MOUSE
UniprotKB:
O54917,
Q8VHT4
UniParc:
UPI00000E888B,
UPI00000E8000
EMBL:
AF487711,
AF032131,
AF393247,
AK146792,
AC157352,
AF393246,
AF393248,
AK149061,
AH011236,
BC037656,
AF393245
Ensembl:
ENSMUSG00000057469
KO:
mmu:50496
|
| Nucleutide sequences |
EMBL-CDS:
AAC53521.1,
AAM45941.1,
BAE27435.1,
BAE28727.1,
AAH37656.1,
AAL38217.1
Ensembl_TRS:
ENSMUST00000020908
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020908
RefSeq:
XP_006515212.1,
XP_006515210.1,
XP_036013414.1,
NP_150373.2,
XP_006515211.1
|
| Others |
UniRef100:
UniRef100_O54917,
UniRef100_Q8VHT4
UniRef90:
UniRef90_O75461,
UniRef90_Q8VHT4
UniRef50:
UniRef50_D4ACR8,
UniRef50_O75461
UniGene:
Mm.23296
CCDS:
CCDS36409.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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