| Type | Description |
|---|---|
| Definition | thimet oligopeptidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:24:00 | The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity. | 32079362 |
| 2014-02-22 10:52:00 | the cellular peptidases dipeptidyl peptidase 3 (DPP-3) and thimet oligopeptidase 1 (TOP-1), both of which are present in nonimmunogenic necrotic cells, eliminated proteasomal degradation products and blocked Ag cross-presentation | 24216478 |
| 2010-11-06 10:26:00 | Data show that Thimet oligopeptidase (TOP) is coexpressed with estrogen receptor alpha, and estradiol regulates TOP expression in a brain region-specific manner in female mice. | 20456597 |
| 2010-01-21 00:00:00 | increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta load. | 18571100 |
| 2010-01-21 00:00:00 | Melanoma cells secrete thimet oligopeptidase which have an important role in tumor proliferation/angiogenesis in vitro and in vivo. | 17620116 |
| Type | IDs |
|---|---|
| Synonymous | AI131655, AI327041, EP24.15 |
| Gene |
UniProtKB-ID:
THOP1_MOUSE,
A0A0R4IZY0_MOUSE
UniprotKB:
Q8C1A5,
A0A0R4IZY0
UniParc:
UPI00000E730F,
UPI00000EA1EB
EMBL:
BC031175,
AF314187,
BC031722,
AC152500,
AK028609
Ensembl:
ENSMUSG00000004929
KO:
mmu:50492
|
| Nucleutide sequences |
EMBL-CDS:
AAH31722.1,
BAC26031.1,
AAG35061.1,
AAH31175.1
Ensembl_TRS:
ENSMUST00000005057
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005057
RefSeq:
NP_073144.3
|
| Others |
UniRef100:
UniRef100_Q8C1A5,
UniRef100_A0A0R4IZY0
UniRef90:
UniRef90_P24155
UniRef50:
UniRef50_P24155
UniGene:
Mm.26995
CCDS:
CCDS24042.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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