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50487 PLA2G3

50487

PLA2G3

phospholipase A2 group III

protein-coding

Homo sapiens

基因描述

Type Description
Definition phospholipase A2 group III

研究结论

Date Results Publications
2018-01-20 11:33:00 Several hits were discovered, and data have been uploaded to PubChem. This study describes the first high-throughput optical screening assay for secreted phospholipase A2 inhibitors based on a phospholipid vesicle substrate 27146384
2015-08-22 11:05:00 Studies indicate that the expression of secreted phospholipases A2 (sPLA2s), most notably the group IIA, III and X enzymes, is dysregulated in various malignant tissues. 25286228
2015-08-22 10:19:00 Studies indicate that phospholipase A2 receptor 1 (PLA2R1) may act as a clearance or signaling receptor for secreted phospholipase A2 (sPLA2s). 25230085
2015-08-08 11:14:00 sPLA2GIII expression may be used as a risk factor for lymph node metastasis and a prognostic marker in colorectal cancer. In addition, sPLA2GIII and sPLA2GX may play opposing roles in colorectal carcinogenesis 25964585
2014-05-03 10:36:00 Data indicate that the expression of genes encoding hGIIA, hGIII and hGX sPLA2s (PLA2G2A, PLA2G3 and PLA2G10, respectively) in breast tumour biopsies differs from that in normal tissues. 24508801

名称对应

Type IDs
Synonymous GIII-SPLA2, SPLA2III, sPLA2-III
Gene
UniProtKB-ID: PA2G3_HUMAN
UniprotKB: Q9NZ20
UniParc: UPI00001AE5E4
EMBL: AC005005, BC025316, AF220490
Ensembl: ENSG00000100078
KO: hsa:50487
Nucleutide sequences
EMBL-CDS: AAF44746.1, AAH25316.1, AAD15617.1
Ensembl_TRS: ENST00000215885
Protein sequencees
Ensembl_PRO: ENSP00000215885
RefSeq: XP_011528506.1, XP_011528507.1, NP_056530.2
Others
UniRef100: UniRef100_Q9NZ20
UniRef90: UniRef90_Q9NZ20
UniRef50: UniRef50_Q9NZ20
UniGene: Hs.149623
CCDS: CCDS13889.1

全选

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