| Type | Description |
|---|---|
| Definition | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease. | 32971328 |
| 2020-05-30 13:23:00 | SMARCAL1-deficient induced pluripotent stem cells maintain active DNA damage response beyond differentiation. | 31515241 |
| 2020-01-18 11:48:00 | EXD2 deficiency leads to fork collapse, hypersensitivity to replication inhibitors, and genomic instability. Impeding fork regression by inactivation of SMARCAL1 or removal of RECQ1's inhibition in EXD2(-/-) cells restores efficient fork restart and genome stability. Moreover, purified EXD2 efficiently processes substrates mimicking regressed forks. | 31255466 |
| 2019-06-01 11:50:00 | Downregulation of SMARCAL1 and BRG1 results in downregulation of ATM and ATR and therefore, mitotic abnormalities. | 30317028 |
| 2019-03-16 12:15:00 | Mcm10 is a potent DNA strand-annealing protein that inhibits fork regression by SMARCAL1. | 30598452 |
| Type | IDs |
|---|---|
| Synonymous | HARP, HHARP |
| Gene |
UniProtKB-ID:
SMAL1_HUMAN
UniprotKB:
Q9NZC9
UniParc:
UPI000000DA30
EMBL:
AF210839,
AK000117,
BC016482,
AC098820,
BC043341,
AF210836,
AF210841,
CH471063,
AF082179,
AL122076,
AF432223,
AF210833,
AF210840,
AF210842,
AF210838,
AF210835,
AF210837,
AF210834
Ensembl:
ENSG00000138375
KO:
hsa:50485
|
| Nucleutide sequences |
EMBL-CDS:
AAH43341.1,
AAH16482.1,
AAL73034.1,
AAF70454.1,
AAF24984.1,
AAX93097.1,
CAB59251.1,
EAW70567.1,
BAA90955.1
Ensembl_TRS:
ENST00000357276,
ENST00000358207
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350940,
ENSP00000349823
RefSeq:
NP_001120679.1,
NP_054859.2
|
| Others |
UniRef100:
UniRef100_Q9NZC9
UniRef90:
UniRef90_Q9NZC9
UniRef50:
UniRef50_Q9NZC9
UniGene:
Hs.516674
CCDS:
CCDS2403.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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