| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:12:00 | Paired Basic Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma. | 32449780 |
| 2021-02-13 13:29:00 | Upregulation of PACE4 in prostate cancer is not dependent on E2F transcription factors. | 32119574 |
| 2020-10-31 13:13:00 | PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling. | 31893970 |
| 2020-03-14 10:36:00 | PCSK6, a gene that has been implicated in the ontogenesis of bodily asymmetries by regulating the nodal cascade, is also relevant for structural asymmetries in the human brain. | 31115778 |
| 2018-10-20 11:13:00 | Data suggest that soluble corin lacking transmembrane domain is activated by PCSK6 in conditioned medium or in cell-free system but not intracellularly; cell membrane association is unnecessary for PCSK6 to activate corin; soluble corin and PCSK6 are secreted by cardiomyocytes (or HEK293 cells) via different intracellular pathways. (PCSK6 = proprotein convertase subtilisin/kexin type-6) | 29180304 |
| Type | IDs |
|---|---|
| Synonymous | PACE4, SPC4 |
| Gene |
UniProtKB-ID:
PCSK6_HUMAN,
H7BXT3_HUMAN,
Q59H04_HUMAN,
A2RQD9_HUMAN
UniprotKB:
P29122,
H7BXT3,
Q59H04,
A2RQD9
UniParc:
UPI000002B06A,
UPI000002B069,
UPI00001311D0,
UPI00004F6AF7,
UPI000002B06B,
UPI000002B06F,
UPI0000F0A1A6,
UPI000002B06D,
UPI000016004B,
UPI000002B06C,
UPI000002B06E
EMBL:
M80482,
D87993,
D87994,
D28513,
AC090164,
AB001914,
AC023024,
D87995,
AC087528,
AM491522,
AMYH02031172,
AB208955,
D28514
Ensembl:
ENSG00000140479
KO:
hsa:5046
|
| Nucleutide sequences |
EMBL-CDS:
BAA21625.1,
BAA05871.1,
AAA59998.1,
BAA21793.1,
BAA21623.1,
BAA21620.1,
BAA21792.1,
BAA21627.1,
BAA21626.1,
BAA21624.1,
BAA21622.1,
BAA05872.1,
BAA21621.1,
BAA21791.1,
BAD92192.1,
CAM33226.1
Ensembl_TRS:
ENST00000618548,
ENST00000615296,
ENST00000611716,
ENST00000611967,
ENST00000331826
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000479496,
ENSP00000478081,
ENSP00000482760,
ENSP00000477768,
ENSP00000332052
RefSeq:
NP_001278238.1,
NP_612195.1,
NP_612197.1,
NP_612196.1,
NP_002561.1,
NP_612198.2,
NP_612192.1
|
| Others |
UniRef100:
UniRef100_Q59H04,
UniRef100_P09661,
UniRef100_H7BXT3,
UniRef100_P29122
UniRef90:
UniRef90_P09661,
UniRef90_P29122,
UniRef90_H7BXT3
UniRef50:
UniRef50_P29122-4,
UniRef50_P29122
UniGene:
Hs.498494,
Hs.665989
CCDS:
CCDS73789.1,
CCDS73793.1,
CCDS73791.1,
CCDS73790.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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