| Type | Description |
|---|---|
| Definition | signal peptide, CUB domain, EGF-like 2 |
| Date | Results | Publications |
|---|---|---|
| 2014-01-11 12:14:00 | Emilin3 modulates the availability of hedgehog ligands by interacting with the permissive factor Scube2 in the notochord sheath | 24131633 |
| 2012-11-03 14:20:00 | Data show that knocking down the function of all three scube genes scube1, scube2 and scube3 simultaneously phenocopies a complete loss of Hedgehog (HH) signal transduction in the embryo. | 22609552 |
| 2010-01-21 00:00:00 | Scube2 can modulate the long-range action of Bmp-dependent Hedgehog signaling in the neural tube and somites. | 15753045 |
| 2010-01-21 00:00:00 | positional cloning and functional studies demonstrate that You is a novel extracellular component of the Hedgehog pathway in vertebrates(You gene) | 15660164 |
| 2010-01-21 00:00:00 | Scube2 may act during Hedgehog signal transduction prior to, or during, receipt of the Hedgehog signal at the plasma membrane | 16626681 |
| Type | IDs |
|---|---|
| Synonymous | wu:fc27f08, you |
| Gene |
UniProtKB-ID:
SCUB2_DANRE,
A0A0B5JWE1_DANRE
UniprotKB:
Q5G872,
A0A0B5JWE1
UniParc:
UPI00004EC2A4,
UPI00004C61ED
EMBL:
KM655721,
AB193554,
AY741664,
DQ438942
KO:
dre:503728
|
| Nucleutide sequences |
EMBL-CDS:
AAW63651.1,
BAD91395.1,
ABD96046.1,
AJG06067.1
|
| Protein sequencees |
RefSeq:
XP_021333196.1,
XP_021333197.1,
XP_005166450.1,
XP_005166447.1,
XP_005166448.1,
NP_001014813.1
|
| Others |
UniRef100:
UniRef100_A0A0B5JWE1,
UniRef100_Q5G872
UniRef90:
UniRef90_Q5G872
UniRef50:
UniRef50_Q5G872
UniGene:
Dr.150435
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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