DEFB104B - defensin beta 104B-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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503618 DEFB104B

基因描述

Type	Description
Definition	defensin beta 104B

研究结论

Date	Results	Publications
2014-10-24 10:54:00	Beta-defensin 104 displays antimicrobial activity against S. carnosus, E. coli, S. cerevisiae, and P. aeruginosa (strong).	11481241
2012-08-04 10:52:00	Data suggest an activation of b-defensin-4 induction, in human knee meniscus by the osteoarthritis inflammatory process as a result of an endogenous antibiotic defense mechanism accompanied by an intrinsic effort of tissue remodeling.	21879330
2011-12-10 10:27:00	Our results suggest that copy number variation of DEFB4 may not contribute to the pathogenesis of Behcet's disease.	21385545

名称对应

Type	IDs
Synonymous	BD-4, DEFB-4, hBD-4
Gene	UniProtKB-ID: D104A_HUMAN UniprotKB: Q8WTQ1 UniParc: UPI000013F79C EMBL: BC100850, AJ314835, BC100851, AJ314834, BC100848, BC100849 Ensembl: ENSG00000177023, ENSG00000277006, ENSG00000176782, ENSG00000285034 KO: hsa:503618, hsa:140596
Nucleutide sequences	EMBL-CDS: CAC85511.1, AAI00852.1, AAI00851.1, AAI00850.1, AAI00849.1, CAC85520.1 Ensembl_TRS: ENST00000316169, ENST00000644603, ENST00000314265, ENST00000646913, ENST00000616398
Protein sequencees	Ensembl_PRO: ENSP00000322191, ENSP00000481976, ENSP00000494390, ENSP00000320813, ENSP00000494886 RefSeq: NP_001035792.1
Others	UniRef100: UniRef100_Q8WTQ1 UniRef90: UniRef90_Q8WTQ1 UniRef50: UniRef50_Q8WTQ1 UniGene: Hs.559507, Hs.745562 CCDS: CCDS34812.1, CCDS34834.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
21879330	Expression of Î²-defensin-4 in "an in vivo and ex vivo model" of human osteoarthritic knee meniscus. Knee Surg Sports Traumatol Arthrosc Giuseppe Musumeci , Maria Luisa Carnazza , Rosalia Leonardi , Carla Loreto	2012-02-01	-
21385545	Copy number variation of Î²-defensin genes in BehÃ§et's disease. Clin. Exp. Rheumatol. Jin Joo Park , Boram R Oh , Joung Yeon Kim , Ji Ah Park , Chul Kim , Yun Jong Lee , Yeong Wook Song , John A L Armour , Eun Bong Lee	2011-09-27	DEFB104A, DEFB4A, DEFB104B
16033865	Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiol. Genomics Amar A Patil , Yibin Cai , Yongming Sang , Frank Blecha , Guolong Zhang	2005-09-21	Gm6040, Gm15056, Gm17416, Defb19, Defb36, Defb20, Defb50, Defb21, Defb48, Defb45, Defb22, Defb28, Spag11b, Defb46, Defb42, Defb23, Defa-ps12, Defb33, Defb44-ps, Gm21944, Defa-ps13, Defb26, Defb43, Defb25, Defb18, Gm15386, Defb47, Defb30, Defb41, Spag11a, Defb22, Defb52, Defb29, Defb51, Defb23, Defb16-ps, Defb3, Defb5, Defb13, Defb14, Defb28, Defb26, Defb11, Defb2, Defb24, Defb9, Defb19, Defb10, Defb21, Defb40, Defb50, Defb36, Defb20, Defb27, Defb12, Defb25, Defb15, Defb39, Defb33, Defb41, Defb43, Defb44, Defb49, Defb18, Defb30, Defb42, Defb17, Defb4, Defb37, Defb38, Spag11b, DEFB107A, LOC100170034, DEFB110, DEFB117, DEFB103A, DEFB126, DEFB104, DEFB106A, DEFB105A, DEFB108P, DEFB134, DEFB136, DEFB135, DEFB133, DEFB114, DEFB113, DEFB112, DEFB115, DEFB118, DEFB123, DEFB124, DEFB131, DEFB127, DEFB129, DEFB132, DEFB116, DEFB119, DEFB121
15727258	Evidence for duplication of the human defensin gene DEFB4 in chromosomal region 8p22-23 and implications for the analysis of SNP allele distribution. Genet. Test. Michele Boniotto , Mario Ventura , Joyce Eskdale , Sergio Crovella , Grant Gallagher	2004-09-01	DEFB104A, DEFB4A, DEFB105A, DEFB106A, DEFB107A, DEFB107B, DEFB104B, DEFB106B, DEFB105B
15588320	Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence. BMC Genomics Stefan Taudien , Petra Galgoczy , Klaus Huse , Kathrin Reichwald , Markus Schilhabel , Karol Szafranski , Atsushi Shimizu , Shuichi Asakawa , Adam Frankish , Ivan F Loncarevic , Nobuyoshi Shimizu , Roman Siddiqui , Matthias Platzer	2004-01-01	DEFB104A, DEFT1P, DEFB105A, DEFB106A, DEFB107A, DEFA8P, DEFA9P, DEFB107B, DEFB104B, DEFB106B, DEFB105B, DEFA1A3, DEFA7P, DEFA11P
12916016	Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster. Am. J. Hum. Genet. E J Hollox , J A L Armour , J C K Barber	2003-09-01	-
12734011	Duplication and selection in the evolution of primate beta-defensin genes. Genome Biol. Colin A M Semple , Mark Rolfe , Julia R Dorin	2003-01-01	-
12193721	Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice. J. Immunol. Yasuhiro Yamaguchi , Takahide Nagase , Ryosuke Makita , Shigetomo Fukuhara , Tetsuji Tomita , Takashi Tominaga , Hiroki Kurihara , Yasuyoshi Ouchi	2002-09-01	-
11854508	Discovery of five conserved beta -defensin gene clusters using a computational search strategy. Proc. Natl. Acad. Sci. U.S.A. Brian C Schutte , Joseph P Mitros , Jennifer A Bartlett , Jesse D Walters , Hong Peng Jia , Michael J Welsh , Thomas L Casavant , Paul B McCray	2002-02-19	Defb7, Defb11, Defb15, Defb10, Defb36, DEFB118, DEFB104A, DEFB127, DEFB129, DEFB105A, DEFB106A, DEFB107A, DEFB108B, DEFB109P1, DEFB110, DEFB112, DEFB113, DEFB114, DEFB115, DEFB116, DEFB117, DEFB119, DEFB121, DEFB122, DEFB123, DEFB124, DEFB125, DEFB128, DEFB130, DEFB107B, DEFB104B, DEFB108P1, DEFB108P2, DEFB108P4, DEFB106B, DEFB105B, DEFB108P3, DEFB135, DEFB136, DEFB131, DEFB126

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