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5032 P2RY11

5032

P2RY11

purinergic receptor P2Y11

protein-coding

Homo sapiens

基因描述

Type Description
Definition purinergic receptor P2Y11

研究结论

Date Results Publications
2021-03-27 14:44:00 Frontline Science: P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse. 32531829
2020-10-24 13:55:00 The Human G Protein-Coupled ATP Receptor P2Y11 Is Associated With IL-10 Driven Macrophage Differentiation. 31447857
2020-06-27 11:24:00 Study of eight narcolepsy-associated P2RY11 mutations showed decreased surface expression of the R307W P2Y11 mutant and a surface expression similar to wild type for the other seven mutants in HEK293 cells. 31450027
2020-05-16 12:31:00 Our study provides evidence of a protective mechanism of P2Y11R antagonist NF340 against cytokine-induced inflammation. Therefore, targeting P2Y11R could have potential therapeutic implication in the treatment of rheumatoid arthritis. 31301116
2019-10-19 12:11:00 findings suggest that LPS and ATP accumulation in the circulation of sepsis patients suppresses T cells by promoting inappropriate P2Y11 receptor stimulation that impairs T cell metabolism and functions. 30787105

名称对应

Type IDs
Synonymous P2Y11
Gene
UniProtKB-ID: P2Y11_HUMAN
UniprotKB: Q96G91
UniParc: UPI0000131004
EMBL: AJ298334, AF030335, AY449733, CH471106, AK313550, BC073827, AJ300588, AF498921
Ensembl: ENSG00000244165
KO: hsa:5032
Nucleutide sequences
EMBL-CDS: AAH73827.1, BAG36326.1, AAB88674.1, AAR18077.1, CAC29362.1, CAC18877.1, AAM18130.1, EAW84077.1
Ensembl_TRS: ENST00000321826
Protein sequencees
Ensembl_PRO: ENSP00000323872
RefSeq: NP_002557.2
Others
UniRef100: UniRef100_Q96G91
UniRef90: UniRef90_Q96G91
UniRef50: UniRef50_Q96G91
UniGene: Hs.14468
CCDS: CCDS12226.1

全选

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研究热度

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