| Type | Description |
|---|---|
| Definition | purinergic receptor P2Y2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:32:00 | NLRC4, ASC and Caspase-1 Are Inflammasome Components that Are Mediated by P2Y2R Activation in Breast | 32397236 |
| 2020-04-25 11:10:00 | these findings reveal the roles of the P2RY2 in Pancreatic Ductal Adenocarcinoma metabolic reprogramming, suggesting that P2RY2 might be a potential metabolic therapeutic target for Pancreatic Ductal Adenocarcinoma. | 30420446 |
| 2020-04-04 11:24:00 | Human cytomegalovirus (HCMV) infection elevates the level of purinergic receptor P2Y2. The HCMV IE1 protein induces P2Y2 expression; and P2Y2-mediated signaling is important for efficient HCMV gene expression, DNA synthesis, and the production of infectious HCMV progeny. P2Y2 cooperates with the viral UL37x1 protein to regulate cystolic Ca(2+) levels. P2Y2 also regulates PI3K/Akt signaling and infected cell motility. | 31481624 |
| 2020-03-21 10:39:00 | The authors report a novel role for the purinergic P2Y2 receptor in the sprouting of endothelial cells. | 31278420 |
| 2020-01-11 10:39:00 | Authors describe a mechanism whereby autocrine purinergic signalling and constitutive P2Y2 receptor activation suppresses basal lipolysis in primary human in vitro-differentiated adipocytes. Authors found that human adipocytes possess cytoplasmic Ca(2+) tone due to ATP secretion and constitutive P2Y2 receptor activation. | 30333139 |
| Type | IDs |
|---|---|
| Synonymous | HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R |
| Gene |
UniProtKB-ID:
P2RY2_HUMAN
UniprotKB:
P41231
UniParc:
UPI000013F103
EMBL:
CH471076,
BC028135,
AP002761,
AY136753,
AK313942,
U07225,
BC012104
Ensembl:
ENSG00000175591
KO:
hsa:5029
|
| Nucleutide sequences |
EMBL-CDS:
EAW74882.1,
AAH12104.1,
AAH28135.1,
BAG36660.1,
AAC04923.1,
AAN01279.1
Ensembl_TRS:
ENST00000393597,
ENST00000311131,
ENST00000393596
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310305,
ENSP00000377222,
ENSP00000377221
RefSeq:
NP_788085.3,
NP_002555.4,
XP_016873328.1,
XP_005274077.1,
XP_005274076.1,
XP_005274078.1,
NP_788086.3,
XP_011543376.1
|
| Others |
UniRef100:
UniRef100_P41231
UniRef90:
UniRef90_P41231
UniRef50:
UniRef50_P41232
UniGene:
Hs.339,
Hs.572077
CCDS:
CCDS8219.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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