| Type | Description |
|---|---|
| Definition | purinergic receptor P2X 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:47:00 | New Insights of the Zn(II)-Induced P2 x 4R Positive Allosteric Modulation: Role of Head Receptor Domain SS2/SS3, E160 and D170. | 32971737 |
| 2021-02-20 13:35:00 | Contribution of P2X4 Receptors to CNS Function and Pathophysiology. | 32756482 |
| 2021-02-20 13:34:00 | Resolving the Ionotropic P2X4 Receptor Mystery Points Towards a New Therapeutic Target for Cardiovascular Diseases. | 32679900 |
| 2020-06-27 10:07:00 | Results found that P2X4R was highly expressed in glioblastoma multiforme cell lines. Its depletion suppressed cell survival and proliferation while promoting cell apoptosis through BDNF/TrkB/ATF4 signaling pathway. This study provides the first evidence that P2X4R plays important roles in GBM cell growth and apoptosis. | 30362154 |
| 2020-04-11 11:38:00 | higher expression of P2X4 and P2X7 receptors is significantly associated with the upregulated cellular stress leading to inflammation in hepatobiliary carcinomas | 31401785 |
| Type | IDs |
|---|---|
| Synonymous | P2X4, P2X4R |
| Gene |
UniProtKB-ID:
P2RX4_HUMAN
UniprotKB:
Q99571
UniParc:
UPI0000E23445,
UPI0000D4DAF5,
UPI000002EB24
EMBL:
U87270,
U83993,
U85971,
BT019739,
Y07684,
AF012903,
U85972,
U85973,
AC069209,
AF191093,
AF000234,
U85974,
U85975,
BC033826,
BT019738
Ensembl:
ENSG00000135124
KO:
hsa:5025
|
| Nucleutide sequences |
EMBL-CDS:
AAF06661.1,
CAA68948.1,
AAV38544.1,
AAV38543.1,
AAB66834.1,
AAH33826.1,
AAB58405.1,
AAD00553.1,
AAD00556.1
Ensembl_TRS:
ENST00000337233,
ENST00000359949,
ENST00000542067
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000353032,
ENSP00000438329,
ENSP00000336607
RefSeq:
XP_011536718.1,
NP_001248326.1,
NP_002551.2,
NP_001248327.1,
NP_001243725.1
|
| Others |
UniRef100:
UniRef100_Q99571
UniRef90:
UniRef90_Q99571
UniRef50:
UniRef50_Q99571
UniGene:
Hs.321709
CCDS:
CCDS58282.1,
CCDS9214.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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