| Type | Description |
|---|---|
| Definition | purinergic receptor P2X 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 10:11:00 | The authors used structural, computational and functional approaches to show that a crucial acidic chamber near the nucleotide-binding pocket in human P2X3 receptors accommodates divalent ions in two distinct modes in the absence and presence of nucleotide. | 31232692 |
| 2018-08-18 11:44:00 | Druggable negative allosteric site of P2X3 receptors. | 29674445 |
| 2017-11-11 10:37:00 | conclude that the inter-subunit salt bridge between E112 and R198 of the head and dorsal fin domains, respectively, serves to control the mobility of these domains during agonist-activation of the hP2X3R | 26825305 |
| 2017-10-14 11:08:00 | P2X3 expressions in endometriosis endometrium and endometriotic lesions were significantly higher as compared with control endometrium, and positively correlated with pain. | 28898282 |
| 2017-03-11 12:49:00 | P2X3 receptor expression was up-regulated in neurons from patients with temporal lobe epilepsy. | 26738991 |
| Type | IDs |
|---|---|
| Synonymous | P2X3 |
| Gene |
UniProtKB-ID:
P2RX3_HUMAN
UniprotKB:
P56373
UniParc:
UPI00000342EB
EMBL:
AB016608,
BC074793,
Y07683,
AP000781,
BC109287,
BC074792
Ensembl:
ENSG00000109991
KO:
hsa:5024
|
| Nucleutide sequences |
EMBL-CDS:
AAH74792.1,
AAI09288.1,
AAH74793.1,
BAA76515.1,
CAA68947.1
Ensembl_TRS:
ENST00000263314
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263314
RefSeq:
NP_002550.2,
XP_011543372.1,
XP_011543375.1,
XP_011543371.1,
XP_011543374.1,
XP_011543373.1
|
| Others |
UniRef100:
UniRef100_P56373
UniRef90:
UniRef90_P56373
UniRef50:
UniRef50_P56373
UniGene:
Hs.146738
CCDS:
CCDS7953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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