例如:"NBL1", "4681", "drought"
收藏
5023 P2RX1

5023

P2RX1

purinergic receptor P2X 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition purinergic receptor P2X 1

研究结论

Date Results Publications
2020-10-31 13:16:00 Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism. 31591425
2019-08-10 12:34:00 TgROP18 targets the purinergic receptor P2X1 of the SF268 human neural cells and inhibits ATP-induced apoptosis through the mitochondrial pathway. 31164145
2019-04-13 12:21:00 P2X1 receptors enhance platelet FcgammaRIIa receptor-evoked aggregation through an increase in [Ca(2+)]i downstream of the initial tyrosine phosphorylation events and early dense granule release 29443373
2019-02-16 12:22:00 The importance of this movement was confirmed by demonstrating that substitution introducing positive charge present in the CRH of the hP2X1R causes sensitivity at the normally insensitive rat P2X4R. This study provides a template for developing P2XR subtype selectivity based on the differences among the mammalian subunits around the orthosteric P2XR-binding site and the CRH. 29997254
2017-08-05 12:46:00 Healthy human eosinophils express functional P2X1 receptors whose activation leads to eosinophil alphaMbeta2 integrin-dependent adhesion. P2X1 responses are constitutively reduced in asthmatic compared with healthy eosinophils, probably as the result of an increase in extracellular nucleotide concentration. 27183585

名称对应

Type IDs
Synonymous P2X1
Gene
UniProtKB-ID: P2RX1_HUMAN
UniprotKB: P51575
UniParc: UPI000000DAAB
EMBL: BC044657, U45448, AF177472, X83688, AF020498
Ensembl: ENSG00000108405
KO: hsa:5023
Nucleutide sequences
EMBL-CDS: AAC50698.1, CAA58657.1, AAD55395.1, AAH44657.1, AAC24494.1
Ensembl_TRS: ENST00000225538
Protein sequencees
Ensembl_PRO: ENSP00000225538
RefSeq: XP_011522201.1, XP_011522199.1, NP_002549.1, XP_006721592.1, XP_011522200.1, XP_011522198.1, XP_011522202.1
Others
UniRef100: UniRef100_P51575
UniRef90: UniRef90_P51576
UniRef50: UniRef50_P51576
UniGene: Hs.41735
CCDS: CCDS11040.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员