Type | Description |
---|---|
Definition | purinergic receptor P2X 1 |
Date | Results | Publications |
---|---|---|
2020-10-31 13:16:00 | Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism. | 31591425 |
2019-08-10 12:34:00 | TgROP18 targets the purinergic receptor P2X1 of the SF268 human neural cells and inhibits ATP-induced apoptosis through the mitochondrial pathway. | 31164145 |
2019-04-13 12:21:00 | P2X1 receptors enhance platelet FcgammaRIIa receptor-evoked aggregation through an increase in [Ca(2+)]i downstream of the initial tyrosine phosphorylation events and early dense granule release | 29443373 |
2019-02-16 12:22:00 | The importance of this movement was confirmed by demonstrating that substitution introducing positive charge present in the CRH of the hP2X1R causes sensitivity at the normally insensitive rat P2X4R. This study provides a template for developing P2XR subtype selectivity based on the differences among the mammalian subunits around the orthosteric P2XR-binding site and the CRH. | 29997254 |
2017-08-05 12:46:00 | Healthy human eosinophils express functional P2X1 receptors whose activation leads to eosinophil alphaMbeta2 integrin-dependent adhesion. P2X1 responses are constitutively reduced in asthmatic compared with healthy eosinophils, probably as the result of an increase in extracellular nucleotide concentration. | 27183585 |
Type | IDs |
---|---|
Synonymous | P2X1 |
Gene |
UniProtKB-ID:
P2RX1_HUMAN
UniprotKB:
P51575
UniParc:
UPI000000DAAB
EMBL:
BC044657,
U45448,
AF177472,
X83688,
AF020498
Ensembl:
ENSG00000108405
KO:
hsa:5023
|
Nucleutide sequences |
EMBL-CDS:
AAC50698.1,
CAA58657.1,
AAD55395.1,
AAH44657.1,
AAC24494.1
Ensembl_TRS:
ENST00000225538
|
Protein sequencees |
Ensembl_PRO:
ENSP00000225538
RefSeq:
XP_011522201.1,
XP_011522199.1,
NP_002549.1,
XP_006721592.1,
XP_011522200.1,
XP_011522198.1,
XP_011522202.1
|
Others |
UniRef100:
UniRef100_P51575
UniRef90:
UniRef90_P51576
UniRef50:
UniRef50_P51576
UniGene:
Hs.41735
CCDS:
CCDS11040.1
|
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