| Type | Description |
|---|---|
| Definition | aldehyde dehydrogenase 7 family member A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:46:00 | The study provides first evidence that the saccharopine pathway is the major route of lysine degradation in cultured human brain cells. These results support inhibition of the saccharopine pathway as a new treatment option for antiquitin deficiency. | 30767241 |
| 2020-06-20 11:23:00 | This report provides a comprehensive overview of known ALDH7A1 mutations that cause pyridoxine dependent epilepsy (PDE), and suggests that PDE may be more common than initially estimated. [review] | 30043187 |
| 2020-01-04 10:09:00 | Data show that NADH generated by aldehyde dehydrogenase 7 family, member A1 protein (ALDH7A1) targets brefeldin-A ADP-ribosylated substrate (BARS; CTBP1) to inhibit Coat Protein I (COPI) vesicle fission. | 31492851 |
| 2019-06-29 11:13:00 | Results suggest the NAD+ cofactor of aldehyde dehydrogenase 7 family member A1 protein (ALDH7A1) dramatically enhances tetramerization of the enzyme. | 30184263 |
| 2019-03-23 11:37:00 | Low ALDH7A1 protein levels correlated with poor clinical outcome. | 30486822 |
| Type | IDs |
|---|---|
| Synonymous | ATQ1, EPD, PDE |
| Gene |
UniProtKB-ID:
AL7A1_HUMAN
UniprotKB:
P49419
UniParc:
UPI000013E425,
UPI0000D4C5DE,
UPI00020CDF33
EMBL:
AC099513,
AK297365,
BC073174,
AC093535,
AF002696,
AK312459,
AK295526,
S74728,
BC071712,
BC002515
Ensembl:
ENSG00000164904
KO:
hsa:501
|
| Nucleutide sequences |
EMBL-CDS:
AAH02515.3,
BAG58439.1,
AAH71712.1,
AAB31966.1,
AAH73174.1,
BAG59812.1,
BAG35366.1,
AAC51935.1
Ensembl_TRS:
ENST00000409134,
ENST00000553117
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000387123,
ENSP00000448593
RefSeq:
NP_001189333.2,
NP_001188306.1,
NP_001173.2
|
| Others |
UniRef100:
UniRef100_P49419
UniRef90:
UniRef90_P49419
UniRef50:
UniRef50_P49419
UniGene:
Hs.483239
CCDS:
CCDS56380.2,
CCDS4137.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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