| Type | Description |
|---|---|
| Definition | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:10:00 | Dorsal root ganglion (DRG)-specific knockdown of Magi-1 attenuated thermal nociception and acute inflammatory pain and NaV1.8 protein expression. Magi-1 bound to Slack potassium channels, macrocomplexing with NaV1.8 channels.Magi-1 is an essential scaffold for ion transport in DRG neurons and a central player in pain.Magi-1 is expressed in small- and medium-sized DRG neurons, their axonal tracts, and nodes of Ranvier. | 30860870 |
| 2012-11-24 11:01:00 | MAGI-1 was expressed in Purkinje cells, in hypocampal neurons in CA1 region, in the glomerulus region of olfactory bulb, and at the dorsal root entry zone in embryonic rat spinal cord | 22605569 |
| 2011-12-09 10:58:00 | These results demonstrate that the phosphorylation-dependent scaffolding of the basolateral K(+) channels by MAGI-1a-long participates in the renal regulation of the fluid and electrolyte homeostasis. | 18303016 |
| 2011-07-02 10:25:00 | These data suggest that MAGI-1 regulates surface expression of GLT-1 and the level of glutamate in the hippocampus | 21426345 |
| Type | IDs |
|---|---|
| Synonymous | BAP-1, Baiap1, MAGI-1 |
| Gene |
UniProtKB-ID:
MAGI1_RAT
UniprotKB:
Q4L1J4
UniParc:
UPI000054C067,
UPI000163AC56
EMBL:
AY598951,
AY598952
KO:
rno:500261
|
| Nucleutide sequences |
EMBL-CDS:
AAT99089.1,
AAT99088.1
|
| Protein sequencees |
RefSeq:
XP_006236991.1,
XP_017448321.1,
NP_001025216.1,
XP_006236990.1,
XP_008761355.1,
XP_006236989.1
|
| Others |
UniRef100:
UniRef100_Q4L1J4
UniRef90:
UniRef90_Q96QZ7-5
UniRef50:
UniRef50_Q96QZ7-5
UniGene:
Rn.95239
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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