| Type | Description |
|---|---|
| Definition | solute carrier family 22 member 18 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 11:29:00 | These results suggest that SLC22A18 may act as a tumor suppressor by regulating the expression levels of cell growth-related proteins, and vinca alkaloids might show therapeutic efficacy against low-SLC22A18-expressing breast cancer. | 30145211 |
| 2019-01-26 10:56:00 | suppression of SLC22A18 decreased the supply of intracellular free fatty acids from triglyceride-rich lipid droplets by impairing the lysosomal/autophagy degradation pathway and reduced the invasive activity of HepG2 cells by decreasing IGFBP-1 expression | 30635741 |
| 2017-08-26 11:36:00 | Data provide evidence that SLC22A18 and/or CDKN1C are tumor modifier genes involved in the tumorigenesis of SDHD-mutated paraganglioma. | 27402879 |
| 2016-07-30 11:29:00 | Establish SLC22A18 as a tumor suppressor in colon epithelial cells and propose that SLC22A18 is potentially a marker of diagnostic and prognostic values. | 26196590 |
| 2015-11-21 10:54:00 | microRNA-137 functions as a tumor suppressor in human non-small cell lung cancer by targeting SLC22A18 | 25498886 |
| Type | IDs |
|---|---|
| Synonymous | BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A |
| Gene |
UniProtKB-ID:
S22AI_HUMAN,
E9PRM7_HUMAN
UniprotKB:
Q96BI1,
E9PRM7
UniParc:
UPI0000D4DDA2,
UPI0000070F3F
EMBL:
AF030302,
AF070479,
BC015571,
AF028738,
AF059663,
AF037064,
AB012083,
AC013791
Ensembl:
ENSG00000110628
KO:
hsa:5002
|
| Nucleutide sequences |
EMBL-CDS:
AAH15571.1,
BAA32779.1,
AAB82727.1,
AAC17492.1,
AAC23505.1,
AAC14725.1,
AAC04787.1
Ensembl_TRS:
ENST00000649076,
ENST00000347936,
ENST00000380574,
ENST00000449793
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497561,
ENSP00000307859,
ENSP00000369948,
ENSP00000392072
RefSeq:
NP_899056.2,
NP_001302430.1,
XP_011518444.2,
NP_002546.3,
NP_001302431.1,
XP_011518443.2
|
| Others |
UniRef100:
UniRef100_E9PRM7,
UniRef100_Q96BI1
UniRef90:
UniRef90_Q96BI1,
UniRef90_E9PRM7
UniRef50:
UniRef50_F1PUT8,
UniRef50_Q96BI1
UniGene:
Hs.50868
CCDS:
CCDS7740.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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