Ppp1r3a - protein phosphatase 1, regulatory subunit 3A-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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500036 Ppp1r3a

基因描述

Type	Description
Definition	protein phosphatase 1, regulatory subunit 3A

研究结论

Date	Results	Publications
2019-07-06 13:00:00	RNA sequencing after Ppp1r3a knockdown in primary cultured neonatal rat ventricular myocytes validates network-based predictions and establish Ppp1r3a as a central regulator in heart failure.	31235787
2016-11-05 11:43:00	Rg1 through modulation of GDH and MFN2 maintained mitochondrial dynamics that resulted in protection against H/R-induced cardiomyocyte injury. All these results put forward a new protective mechanism of Rg1 on the therapeutic potential in cardiac I/R disorders.	26593335

名称对应

Type	IDs
Synonymous	RGD1561312
Gene	UniProtKB-ID: D3ZM60_RAT UniprotKB: D3ZM60 UniParc: UPI000021DDE2 EMBL: CH473959, AABR07059912 Ensembl: ENSRNOG00000059350 KO: rno:500036
Nucleutide sequences	EMBL-CDS: EDM15096.1 Gene_ORFName: rCG_27965 Ensembl_TRS: ENSRNOT00000085596
Protein sequencees	Ensembl_PRO: ENSRNOP00000071537 RefSeq: XP_008760939.1, NP_001102692.1
Others	UniRef100: UniRef100_D3ZM60 UniRef90: UniRef90_D3ZM60 UniRef50: UniRef50_Q16821 UniGene: Rn.29809

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
31235787	Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure. Nat Commun Pablo Cordero , Victoria N Parikh , Elizabeth T Chin , Ayca Erbilgin , Michael J Gloudemans , Ching Shang , Yong Huang , Alex C Chang , Kevin S Smith , Frederick Dewey , Kathia Zaleta , Michael Morley , Jeff Brandimarto , Nicole Glazer , Daryl Waggott , Aleksandra Pavlovic , Mingming Zhao , Christine S Moravec , W H Wilson Tang , Jamie Skreen , Christine Malloy , Sridhar Hannenhalli , Hongzhe Li , Scott Ritter , Mingyao Li , Daniel Bernstein , Andrew Connolly , Hakon Hakonarson , Aldons J Lusis , Kenneth B Margulies , Anna A Depaoli-Roach , Stephen B Montgomery , Matthew T Wheeler , Thomas Cappola , Euan A Ashley	2019-06-24	-
26593335	Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2. Mitochondrion Gengting Dong , Tingbo Chen , Xuecong Ren , Zhifeng Zhang , Weixue Huang , Liang Liu , Pei Luo , Hua Zhou	2016-01-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
14715909	Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol. Rev. Hugo Ceulemans , Mathieu Bollen	2004-01-01	Ppp1r3b, Ppp1ca, Ppp1cc, Ppp1cb, Ppp1r3a
12831406	Male preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locus. BMC Genet. Alex S F Doney , Bettina Fischer , Joanne E Cecil , Patricia T W Cohen , Douglas I Boyle , Graham Leese , Andrew D Morris , Colin N A Palmer	2003-06-28	Ppp1r3a
12118251	Digenic inheritance of severe insulin resistance in a human pedigree. Nat. Genet. David B Savage , Maura Agostini , InÃªs Barroso , Mark Gurnell , Jian'an Luan , Aline Meirhaeghe , Anne-Helen Harding , Gudrun Ihrke , Odelia Rajanayagam , Maria A Soos , Stella George , Dirk Berger , E Louise Thomas , Jimmy D Bell , Karim Meeran , Richard J Ross , Antonio Vidal-Puig , Nicholas J Wareham , Stephen O'Rahilly , V Krishna K Chatterjee , Alan J Schafer	2002-08-01	-
11793847	The association between PPP1R3 gene polymorphisms and type 2 diabetes mellitus. Chin. Med. J. G Wang , R Qian , Q Li , T Niu , C Chen , X Xu	2001-12-01	Ppp1r3a, PPP1R3A
10868947	Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity. Diabetes L Hansen , R Reneland , L Berglund , S K Rasmussen , T Hansen , H Lithell , O Pedersen	2000-02-01	-
10389856	The 3'-untranslated region polymorphism of the gene for skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in the type 2 diabetic Japanese population. Diabetes H Maegawa , K Shi , H Hidaka , N Iwai , Y Nishio , K Egawa , H Kojima , M Haneda , H Yasuda , Y Nakamura , M Kinoshita , R Kikkawa , A Kashiwagi	1999-07-01	-
9814479	Variation in the AU(AT)-rich element within the 3'-untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians. J. Clin. Endocrinol. Metab. R A Hegele , S B Harris , B Zinman , J Wang , H Cao , A J Hanley , L C Tsui , S W Scherer	1998-11-01	Ppp1r3a

研究热度

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