| Type | Description |
|---|---|
| Definition | origin recognition complex subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:08:00 | A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins. | 32989049 |
| 2020-07-25 10:19:00 | The circ_ORC2 binds with miR-19a and enhances its expression, thereby inhibiting downstream PTEN expression and activating Akt pathway to promote osteosarcoma cell growth and invasion. | 31103262 |
| 2017-11-04 12:11:00 | The authors have discovered that human cell lines in culture proliferate with intact chromosomal origins of replication after disruption of both alleles of ORC2 or of the ATPase subunit, ORC1. | 27906128 |
| 2017-05-20 13:27:00 | the ORC2 complex with E2 restricts viral replication in the maintenance phase of the viral replication program | 27701460 |
| 2016-12-24 11:45:00 | ORC2 SUMOylation promotes recruitment of KDM5A to centromeres. | 27052177 |
| Type | IDs |
|---|---|
| Synonymous | ORC2L |
| Gene |
UniProtKB-ID:
ORC2_HUMAN,
A0A024R411_HUMAN
UniprotKB:
Q13416,
A0A024R411
UniParc:
UPI0000130E5A
EMBL:
AY652588,
U40268,
CH471063,
AC005037,
BC014834,
U27459
Ensembl:
ENSG00000115942
KO:
hsa:4999
|
| Nucleutide sequences |
EMBL-CDS:
AAH14834.1,
EAW70228.1,
AAB33970.1,
AAY14725.1,
AAC50326.2,
AAT46690.1,
EAW70229.1
Gene_ORFName:
hCG_16554
Ensembl_TRS:
ENST00000234296
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000234296
RefSeq:
XP_011509554.1,
XP_011509555.1,
XP_006712618.1,
NP_006181.1
|
| Others |
UniRef100:
UniRef100_Q13416
UniRef90:
UniRef90_Q13416
UniRef50:
UniRef50_Q13416
UniGene:
Hs.444870
CCDS:
CCDS2334.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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