| Type | Description |
|---|---|
| Definition | myocyte enhancer factor 2C |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 11:21:00 | In cardiomyocytes exposed to biomechanical stimulation, FAK accumulates in the nucleus, binds to and upregulates the transcriptional activity of MEF2c through an interaction with the FAK focal adhesion targeting (FAT) domain. | 27427476 |
| 2017-07-08 10:09:00 | MEF2A and MEF2D were absolutely required for cardiomyocyte survival, whereas MEF2C, despite its major role in cardiac morphogenesis and direct reprogramming, was dispensable for this process. | 28473466 |
| 2015-03-21 13:17:00 | Mef2c expression was sharply increased in compensating phase of right ventricular heart failure but lost in decompensation phase. | 25287062 |
| 2014-08-16 10:38:00 | MEF2C expression in cardiac myocytes is inhibited by suppression of bone morphogenetic protein (BMP)2 expression levels. | 23632743 |
| 2013-06-29 12:43:00 | while loss of delta-catenin does not alter the expression levels of endogenous Mef2, expression of Mef2 in neurons that are knocked down for delta-catenin promotes spine elimination. | 23328440 |
| Type | IDs |
|---|---|
| Synonymous | RGD1563119 |
| Gene |
UniProtKB-ID:
MEF2C_RAT,
A0A096MJ09_RAT,
A0A096MKI4_RAT,
A0A096MK43_RAT,
A0A096MK01_RAT,
A0A096MK88_RAT
UniprotKB:
A0A096MJY4,
A0A096MJ09,
A0A096MKI4,
A0A096MK43,
A0A096MK01,
A0A096MK88
UniParc:
UPI000391AD35,
UPI00001A41CD,
UPI000391AD37,
UPI00001A41CE,
UPI00001A41CF,
UPI00001A41D0
EMBL:
AABR07007384,
CH473955
Ensembl:
ENSRNOG00000033134
KO:
rno:499497
|
| Nucleutide sequences |
EMBL-CDS:
EDM09958.1,
EDM09960.1,
EDM09957.1,
EDM09962.1
Gene_ORFName:
rCG_44705,
rCG_44705
Ensembl_TRS:
ENSRNOT00000076710,
ENSRNOT00000076992,
ENSRNOT00000076230,
ENSRNOT00000076239,
ENSRNOT00000076408,
ENSRNOT00000076084
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000068307,
ENSRNOP00000067948,
ENSRNOP00000068527,
ENSRNOP00000068373,
ENSRNOP00000068328,
ENSRNOP00000068421
RefSeq:
XP_006224019.1,
XP_008773249.1,
XP_017446653.1,
XP_017449843.1,
XP_017446655.1,
XP_017449868.1,
XP_006224017.1,
XP_006231793.1,
XP_006231795.1,
XP_017449861.1,
XP_017446654.1,
XP_017446656.1,
XP_008758864.1,
XP_017449863.1,
XP_017446652.1,
XP_017446657.1,
XP_017449856.1,
XP_017449865.1
|
| Others |
UniRef100:
UniRef100_A0A096MJ09,
UniRef100_A0A096MK01,
UniRef100_A0A096MJY4,
UniRef100_A0A096MK43,
UniRef100_A0A096MK88,
UniRef100_A0A096MKI4
UniRef90:
UniRef90_Q8CFN5-4,
UniRef90_Q06413
UniRef50:
UniRef50_Q06413,
UniRef50_Q8CFN5
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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