Fxn - frataxin-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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499335 Fxn

基因描述

Type	Description
Definition	frataxin

研究结论

Date	Results	Publications
2015-05-16 10:56:00	frataxin deficiency in neonatal rat ventricular myocytes leads to mitochondrial dysfunction and oxidative stress, which would affect lipid metabolism.	24751525
2014-11-29 10:04:00	Frataxin depletion caused mitochondrial membrane potential decrease, neurite degeneration and apoptotic cell death.	24242291
2012-01-28 12:24:00	dual, pro-proliferative but chemosensitizing role in astrocytic tumors	21863062

名称对应

Type	IDs
Synonymous	RGD1565754
Gene
Nucleutide sequences
Protein sequencees	RefSeq: NP_001178881.1
Others	UniGene: Rn.13133

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
29491838	Iron Sulfur and Molybdenum Cofactor Enzymes Regulate the Drosophila Life Cycle by Controlling Cell Metabolism. Front Physiol Zvonimir Marelja , Silke LeimkÃ¼hler , Fanis Missirlis	2018-01-01	-
24751525	Frataxin deficiency in neonatal rat ventricular myocytes targets mitochondria and lipid metabolism. Free Radic. Biol. Med. Ãlia Obis , VerÃ³nica Irazusta , Daniel SanchÃs , Joaquim Ros , Jordi Tamarit	2014-08-01	Fxn
24242291	Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein. Hum. Mol. Genet. Stefka Mincheva-Tasheva , Elia Obis , Jordi Tamarit , Joaquim Ros	2014-04-01	Fxn
21863062	Dual role of the mitochondrial protein frataxin in astrocytic tumors. Lab. Invest. Elmar Kirches , Nadine Andrae , Aline Hoefer , Barbara Kehler , Kim Zarse , Martin Leverkus , Gerburg Keilhoff , Peter Schonfeld , Thomas Schneider , Annette Wilisch-Neumann , Christian Mawrin	2011-12-01	Fxn, Fxn, FXN
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20053667	Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin. Hum Mol Genet Ivano CondÃ² , Florence Malisan , Ilaria Guccini , Dario Serio , Alessandra Rufini , Roberto Testi	2010-04-01	-
18809400	Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy. Exp. Neurol. Giorgia Melli , Michela Taiana , Francesca Camozzi , Daniela Triolo , Paola Podini , Angelo Quattrini , Franco Taroni , Giuseppe Lauria	2008-12-01	Fxn
18424449	Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia. Hum. Mol. Genet. Kuanyu Li , Edward K Besse , Dung Ha , Gennadiy Kovtunovych , Tracey A Rouault	2008-08-01	FXN
18614015	A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha	2008-07-11	Acacb, Hscb, Gadd45gip1, Lars2, Acad11, Chchd10, Nt5dc3, Slc25a41, Nt5m, Cyp27a1, Acly, Ndufb11, Gldc, Rexo2, Rars, Aldh6a1, Slc25a47, Rdh14, Ppif, Ldhal6b, Me2, Glyat, Slc25a45, Acaca, Nt5c3, Mrpl10, Mrpl41, Mrpl30, Aldh1l1, Mthfs, Shmt2, Atic, Mthfd1, Mat2b, Fam210a, Gpt2, Lyrm2, Rdh13, Mtrf1l, Atad3a, Rars2, Sccpdh, Me3, Maob, Dut, Cyp11b1, Fdps, Akr7a5, Msra, Krt5, Cox6b1, Qdpr, Acat1, Acat2, Aldh7a1, Pcca, Etfb, Etfa, Nudt19, Acadl, Acadm, Acadvl, Acaa1a, Acads, Aco1, Aco2, Prosc, Afg3l1, Adsl, Agxt, Ak2, Ak4, Akap1, Alas1, Alas2, Abcd1, Aldh2, Aldh3a2, Gfer, Acsm1, Slc25a4, Slc25a5, Prdx3, Prdx6, Mrps2, Arg2, Rhoa, Atp5a1, Atp5b, Atp5c1, Atp5f1, Atp5g1, Atp5j, Atp5k, Atpif1, Auh, Akr1b7, Bad, Bak1
18537827	Dynamics, stability and iron-binding activity of frataxin clinical mutants. FEBS J. Ana R Correia , Chiara Pastore , Salvatore Adinolfi , Annalisa Pastore , ClÃ¡udio M Gomes	2008-07-01	-

研究热度

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