| Type | Description |
|---|---|
| Definition | opioid related nociceptin receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 11:53:00 | Decreased Nociceptin Receptors Are Related to Resilience and Recovery in College Women Who Have Experienced Sexual Violence. Decreased midbrain and cerebellum nociceptin receptors are associated with less severe PTSD symptoms. Medications that target nociceptin should be explored to prevent and treat PTSD. | 30954231 |
| 2019-10-26 10:36:00 | Low methylation levels in intron 1 of OPRL1 are associated with higher psychosocial stress and higher frequency of binge drinking, an effect mediated by OPRL1 methylation: in individuals with low methylation of OPRL1, frequency of binge drinking is associated with stronger BOLD response in the ventral striatum during reward anticipation. | 29197086 |
| 2019-10-26 10:32:00 | NOP-R is expressed on epidermal keratinocytes in pachyonychia congenita. Robust NOP-R expression was detected in epidermal keratinocytes and in a subset of PGP9.5+ fibers in both epidermis and dermis. NOP-R expression in keratinocytes was reduced in -affected plantar skin vs unaffected skin. Expression occurred in dermal NFH+ myelinated fibers in all groups, and SP+ fibers, but few CGRP+ fibers co-expressed it. | 30255608 |
| 2019-09-21 11:14:00 | Nociceptin receptor ORL1 increases the cell surface expression of reticulon 4 receptor (NgR1) in HEK293T cells. | 29615517 |
| 2019-02-02 11:38:00 | the present findings on OPRM1 and OPRL1 methylation together with our previous study on OPRK1 and OPRD1, suggest an epigenetic involvement of the opioid system in AD, and a potential diagnostic value of opioid receptor methylation for AD. | 30152845 |
| Type | IDs |
|---|---|
| Synonymous | KOR-3, NOCIR, NOP, NOPr, OOR, ORL1 |
| Gene |
UniProtKB-ID:
OPRX_HUMAN,
Q8IXB0_HUMAN,
A0A5F9ZI64_HUMAN
UniprotKB:
P41146,
Q8IXB0,
A0A5F9ZI64
UniParc:
UPI000002B023,
UPI0007425AD9,
UPI00000743E5,
UPI0000001C6D
EMBL:
CR542061,
AL590548,
AF126470,
AY268428,
AF115266,
AF348323,
X77130,
AL121581,
BC038433,
U30185,
L40949
Ensembl:
ENSG00000125510
KO:
hsa:4987
|
| Nucleutide sequences |
EMBL-CDS:
CAA54386.1,
CAG46858.1,
AAH38433.1,
AAL54890.1,
AAA96251.1,
AAP23195.1,
AAK11714.1,
AAA84913.1,
AAO13224.1
Ensembl_TRS:
ENST00000336866,
ENST00000349451,
ENST00000355631,
ENST00000672146
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000336843,
ENSP00000347848,
ENSP00000336764,
ENSP00000500894
RefSeq:
XP_016883344.1,
NP_000904.1,
NP_001305783.1,
NP_001305784.1,
XP_016883343.1,
XP_011527130.1,
NP_001186948.1,
XP_011527132.1,
NP_872588.1,
NP_001305782.1,
XP_016883342.1
|
| Others |
UniRef100:
UniRef100_Q8IXB0,
UniRef100_P41146
UniRef90:
UniRef90_P41146,
UniRef90_H0VSC3
UniRef50:
UniRef50_P41146
UniGene:
Hs.2859,
Hs.736944
CCDS:
CCDS13556.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员