| Type | Description |
|---|---|
| Definition | cornulin |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 10:25:00 | knockdown of CRNN by small interfering RNA suppressed G1/S transition and attenuated the M5-induced proliferation. In addition, CRNN overexpression increased the phosphorylation and activation of phosphoinositide 3-kinase and Akt. Inactivation of the phosphoinositide 3-kinase and Akt pathways using small interfering RNA or selective inhibitors (LY294002 and MK2206) reduced the proliferative effects of CRNN | 30009832 |
| 2017-07-01 10:07:00 | This study showed a significant correlation between LOH/MSI at 1q21.3 with clinical outcomes and that downregulation of CRNN gene could be considered as a prognostic marker of OSCC. | 25846277 |
| 2017-04-01 11:05:00 | The single-nucleotide polymorphisms of CRNN (rs941934) and RPTN (rs3001978, rs28441202) may contribute to Atopic Dermatitis development, but further studies on a larger group of Atopic Dermatitis patients are needed to verify this assumption. | 28219068 |
| 2014-06-28 11:47:00 | Loss of CRNN expression correlated with advanced tumor length, greater tumor invasion depth, lymph node metastasis, and poor survival in patients with esophageal squamous cell carcinoma. | 24263008 |
| 2014-02-22 10:47:00 | Findings demonstrate that CRNN is a tumor suppressor gene that plays a critical tumor suppressive role in ESCC. | 23894350 |
| Type | IDs |
|---|---|
| Synonymous | C1orf10, DRC1, PDRC1, SEP53 |
| Gene |
UniProtKB-ID:
CRNN_HUMAN
UniprotKB:
Q9UBG3
UniParc:
UPI000006E106
EMBL:
BC030807,
AK316568,
AF077831,
AL135842,
AF185276,
CH471121
Ensembl:
ENSG00000143536
KO:
hsa:49860
|
| Nucleutide sequences |
EMBL-CDS:
AAF00514.1,
BAG38157.1,
EAW53381.1,
AAD55747.1,
AAH30807.1
Ensembl_TRS:
ENST00000271835
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000271835
RefSeq:
NP_057274.1
|
| Others |
UniRef100:
UniRef100_Q9UBG3
UniRef90:
UniRef90_Q9UBG3
UniRef50:
UniRef50_Q9UBG3
UniGene:
Hs.242057
CCDS:
CCDS1010.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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