| Type | Description |
|---|---|
| Definition | ATP synthase F1 subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 12:50:00 | Poly(GR) bound preferentially to the mitochondrial complex V component ATP5A1 and enhanced its ubiquitination and degradation, consistent with reduced ATP5A1 protein level in both (GR)80 mouse neurons and amyotrophic lateral sclerosis and frontotemporal dementia patient brains | 31086314 |
| 2019-01-12 12:00:00 | The study demonstrates a novel role of FANCD2 in governing cellular ATP production via ATP5A, and advances the understanding of how defective Fanconi anemia signaling contributes to aging and cancer at the energy metabolism level. | 28687786 |
| 2019-01-12 11:48:00 | 17% of prostate carcinomas and 18% of benign prostate tissues showed isolated or combined deficiency of oxidative phosphorylation complexes. ATP5F1A, a complex V protein, was the most frequently affected subunit | 30538797 |
| 2018-09-08 11:56:00 | Using systems biology techniques to study gene coexpression network, ATP5A1 was identified and found highly expressed in normal kidney than clear cell renal cell carcinoma (ccRCC) tissues of each grade. Functional and pathway enrichment analysis demonstrated that ATP5A1 is overrepresented in pathway of oxidative phosphorylation, which associated with tumorigenesis and tumor progression. | 29207195 |
| 2017-10-28 13:15:00 | This cohort study showed that the ATP5A1 gene was down regulation between patients with idiopathic Parkinson disease and controls | 28916538 |
| Type | IDs |
|---|---|
| Synonymous | ATP5A, ATP5A1, ATP5AL2, ATPM, COXPD22, HEL-S-123m, MC5DN4, MOM2, OMR, ORM, hATP1 |
| Gene |
UniProtKB-ID:
ATPA_HUMAN,
V9HW26_HUMAN
UniprotKB:
P25705,
V9HW26
UniParc:
UPI00003CEFBB,
UPI000258D167,
UPI000006221A
EMBL:
D28126,
AK302272,
BC007299,
BC016046,
BC039135,
BC019310,
BC003119,
FJ224309,
BT007209,
AK092735,
BC064562,
X59066,
X65460,
CH471088,
AC012569,
BC008028,
D14710,
BC067385,
BC011384,
AK289457
Ensembl:
ENSG00000152234
KO:
hsa:498
|
| Nucleutide sequences |
EMBL-CDS:
AAH16046.1,
BAG52604.1,
AAP35873.1,
BAG63618.1,
BAF82146.1,
AAH64562.1,
AAH19310.1,
AAH03119.1,
AAH11384.1,
CAA41789.1,
AAH07299.1,
AAH39135.2,
AAH67385.1,
BAA03531.1,
BAA05672.1,
CAA46452.1,
AAH08028.2,
EAX01471.1,
ACI46001.1
Gene_ORFName:
hCG_23783
Ensembl_TRS:
ENST00000590665,
ENST00000593152,
ENST00000282050,
ENST00000398752
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000381736,
ENSP00000282050,
ENSP00000465477,
ENSP00000467037
RefSeq:
NP_001244264.1,
XP_016881278.1,
NP_001001937.1,
NP_001244263.1,
NP_001001935.1,
NP_004037.1
|
| Others |
UniRef100:
UniRef100_P25705
UniRef90:
UniRef90_P25705
UniRef50:
UniRef50_P25705
UniGene:
Hs.298280
CCDS:
CCDS59315.1,
CCDS58620.1,
CCDS11927.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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