Type | Description |
---|---|
Definition | opioid binding protein/cell adhesion molecule like |
Date | Results | Publications |
---|---|---|
2020-10-10 13:00:00 | LINC00619 restricts gastric cancer progression by preventing microRNA-224-5p-mediated inhibition of OPCML. | 32359894 |
2020-09-19 16:31:00 | The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling. | 31577955 |
2020-08-01 11:20:00 | Human opioid-binding protein/cell adhesion molecule (OPCML) is expressed in many tissues and localizes to the plasma membrane. It is a putative tumor suppressor that acts on receptor tyrosine kinases, influencing cell cycle arrest, apoptosis, and migration. Its expression is silenced epigenetically in cancer, inferring potential diagnostic, prognostic, and therapeutic roles. [Review] | 31421903 |
2019-07-20 12:04:00 | OPCML promoter was found to be hypermethylated in esophageal squamous cell carcinoma (ESCC) samples. Hypermethylation of the studied OPCML promoter produced no effect on OPCML protein expression in Grade 2 tumors but revealed downregulation in Grade 3 tumors. Deranged OPCML expression may lead to high-grade ESCC as well as epigenetically regulated genes that may alter the Wnt/beta-catenin and TGF-beta-Smad pathways in ... | 30880778 |
2019-05-18 10:04:00 | OPCML and PTPRG, coordinate to repress AXL-dependent oncogenic signalling. | 29907679 |
Type | IDs |
---|---|
Synonymous | IGLON1, OBCAM, OPCM |
Gene |
UniProtKB-ID:
OPCM_HUMAN,
B7ZLQ0_HUMAN,
A8K0Y0_HUMAN,
B2CZX3_HUMAN
UniprotKB:
Q14982,
B7ZLQ0,
A8K0Y0,
B2CZX3
UniParc:
UPI00001FA6FD,
UPI000189A735,
UPI0000055AE0,
UPI0000E0019D,
UPI00001A9955,
UPI000172CB73
EMBL:
EU562299,
BC126251,
EU562297,
BC074773,
AP004606,
BC117254,
AK299908,
AP004782,
BC143946,
AP003029,
AP005638,
AP000903,
EU562300,
BC143945,
AK316491,
EU562298,
CH471065,
AP000863,
AP000843,
AP003784,
AK316273,
L34774,
AP005122,
EU562295,
AP005133,
EU562296,
AK289695,
AP003972,
BX537377
Ensembl:
ENSG00000183715
KO:
hsa:4978
|
Nucleutide sequences |
EMBL-CDS:
ACB56656.1,
ACB56659.1,
CAD97619.1,
ACB56657.1,
AAI26252.1,
BAH14862.1,
AAA36387.1,
AAH74773.1,
AAI17255.1,
BAG61748.1,
AAI43947.1,
AAI43946.1,
EAW67804.1,
BAF82384.1,
ACB56655.1,
ACB56660.1,
BAH14644.1,
ACB56658.1
Gene_ORFName:
hCG_1811667
Ensembl_TRS:
ENST00000331898,
ENST00000612177,
ENST00000541867,
ENST00000524381,
ENST00000374778
|
Protein sequencees |
Ensembl_PRO:
ENSP00000363910,
ENSP00000330862,
ENSP00000482061,
ENSP00000434750,
ENSP00000445496
RefSeq:
NP_002536.1,
NP_001306035.1,
NP_001306032.1,
XP_011541158.1,
NP_001306033.1,
NP_001012393.1,
XP_006718909.1,
NP_001306034.1
|
Others |
UniRef100:
UniRef100_Q14982,
UniRef100_B7ZLQ0
UniRef90:
UniRef90_B7ZLQ0,
UniRef90_Q14982
UniRef50:
UniRef50_Q9P121,
UniRef50_P32736
UniGene:
Hs.4817
CCDS:
CCDS31722.1,
CCDS8492.1,
CCDS81649.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员