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497672 Brca1

497672

Brca1

BRCA1, DNA repair associated

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition BRCA1, DNA repair associated

研究结论

Date Results Publications
2019-03-02 10:52:00 BRCA1 offers prominent functional roles in neurons and glial cells including key support for their physical and molecular integrity. 28585187
2018-09-01 11:15:00 Study indicates that alterations in the localization of BRCA1 protein occur in preneoplastic lesions of the DMBA-rat model of mammary gland carcinogenesis. While no change in the level of BRCA1 protein was detected, its translocation from the cytoplasm to nucleus is blocked during breast cancer progression. 29498408
2017-06-24 10:16:00 NPR3 protects cardiomyocytes from apoptosis through inhibition of cytosolic BRCA1 and TNF-alpha, which are regulators of apoptosis. 27494651
2010-10-30 10:15:00 Promoter regions of Brca1 are modified by soy estrogens in prostate cancer cells. 20668305
2010-09-20 11:19:00 Akt prevents the translocation of BRCA1 to DNA damage foci and, thereby, inhibits the activation of Chk1 following DNA damage 20495005

名称对应

Type IDs
Gene
UniProtKB-ID: BRCA1_RAT, G3V8S5_RAT
UniprotKB: O54952, G3V8S5
UniParc: UPI00001D0604, UPI00000E8761
EMBL: S82500, AC123346, S82504, S82502, U60523, CH473948, AC095278, AF036760
Ensembl: ENSRNOG00000020701
KO: rno:497672
Nucleutide sequences
EMBL-CDS: AAC36493.1, AAB40387.1, AAB37501.1, EDM06137.1
Gene_ORFName: rCG_34321
Ensembl_TRS: ENSRNOT00000083111, ENSRNOT00000028109
Protein sequencees
Ensembl_PRO: ENSRNOP00000072366, ENSRNOP00000028109
RefSeq: XP_008766314.1, NP_036646.1
Others
UniRef100: UniRef100_O54952, UniRef100_G3V8S5
UniRef90: UniRef90_O54952
UniRef50: UniRef50_P48754
UniGene: Rn.48840, Rn.217584

全选

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研究热度

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