例如:"NBL1", "4681", "drought"
收藏
497010 Eng

497010

Eng

endoglin

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition endoglin

研究结论

Date Results Publications
2018-10-20 11:59:00 Study demonstrates that gestational glucocorticoid (GC) exposure during late pregnancy induced impaired glucose homeostasis that is accompanied by increased endoglin levels, atherogenic dyslipidemia and pancreatic beta cell dysfunction, increased DPP-4 activity and altered foetal outcome. Therefore, GC-induced glucose deregulation and inflammation during late gestation is through endoglin-/DPP-4-dependent pathway. 29677638
2017-10-21 12:54:00 In this study, we have shown that ENG inhibition and at the same time up-regulation of COUP-TFII expression promotes intussusceptive angiogenesis. 28859090
2017-10-07 12:40:00 findings demonstrate that intrauterine exposure to an adenovirus overexpressing sENG disrupts lung development by impairing Smad1/5-eNOS signaling. We speculate that sENG-mediated dysregulation of Smad1/5-eNOS signaling contributes to impaired lung development and potentially primes the developing lung for further postnatal insults. 28590142
2017-04-15 10:57:00 Endoglin is expressed mainly by endothelial cells and has been found to be involved in angiogenesis and vascular remodelling. 27822781
2017-01-28 10:17:00 It was confirmed by histopathology and western blotting that COX2 inhibitors, particularly celecoxib, decrease the rate of disease and slow-down progression of existing CRC. These data show that endoglin expression may have an important role in tumor angiogenesis and predict of tumor invasion 27466499

名称对应

Type IDs
Gene
UniProtKB-ID: Q3KR75_RAT, Q6Q3E8_RAT
UniprotKB: Q3KR75, Q6Q3E8
UniParc: UPI00005C2DF3, UPI000035028A
EMBL: AY562420, CH474001, BC105860
KO: rno:497010
Nucleutide sequences
EMBL-CDS: AAI05861.1, AAS67893.1, EDL93221.1
Gene_ORFName: rCG_45763
Protein sequencees
RefSeq: XP_017447460.1, NP_001010968.1
Others
UniRef100: UniRef100_Q3KR75, UniRef100_Q6Q3E8
UniRef90: UniRef90_M0RBA8
UniRef50: UniRef50_Q63961
UniGene: Rn.187025

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员