| Type | Description |
|---|---|
| Definition | oxoglutarate dehydrogenase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:25:00 | Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues. | 32024885 |
| 2020-06-13 10:08:00 | there is the direct interaction between SIRT5 and 2-oxoglutarate dehydrogenase (OGDH), and desuccinylation of OGDH by SIRT5 inhibits the activity of OGDH complex. | 31247190 |
| 2019-02-02 12:10:00 | The data indicate that amino acid/nucleotide metabolism-related genes OGDH, PPAT and PCCA acquire somatic mutations in microsatellite instability-high gastric cancers and colorectal cancers and that mutational intratumoral heterogeneity may occur in at least some of these tumors. | 27468871 |
| 2018-04-28 12:10:00 | PIK3CA mutant cancer cells require PIK3CA but also require the expression of the TCA cycle enzyme 2-oxoglutarate dehydrogenase (OGDH). | 28396387 |
| 2017-07-01 10:28:00 | oxoglutarate dehydrogenase (OGDH) and lipoic acid synthase (LIAS), which when mutated stabilize HIF1alpha in a non-hydroxylated form. | 27923773 |
| Type | IDs |
|---|---|
| Synonymous | AKGDH, E1k, OGDC |
| Gene |
UniProtKB-ID:
ODO1_HUMAN,
B4E3E9_HUMAN,
A0A140VJQ5_HUMAN,
E9PCR7_HUMAN
UniprotKB:
Q02218,
B4E3E9,
A0A140VJQ5,
E9PCR7
UniParc:
UPI00017A8656,
UPI000198CDE7,
UPI000198CDF7,
UPI000006D5FE,
UPI0000070137
EMBL:
BC004964,
AC011894,
BC014617,
CH471128,
D32064,
AC004859,
AK304439,
HM005444,
D10523,
AK304690,
BC009580
Ensembl:
ENSG00000105953
KO:
hsa:4967
|
| Nucleutide sequences |
EMBL-CDS:
BAA01393.1,
AAQ96884.1,
AAH09580.1,
BAA06836.1,
AAH04964.1,
AAQ96885.1,
BAG65261.1,
EAW61086.1,
AAH14617.1,
EAW61087.1,
EAW61089.1,
BAG65461.1,
AEE61042.1
Ensembl_TRS:
ENST00000449767,
ENST00000222673,
ENST00000443864,
ENST00000444676
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000388084,
ENSP00000392878,
ENSP00000222673,
ENSP00000414662
RefSeq:
NP_001158508.1,
NP_002532.2,
NP_001350452.1,
NP_001003941.1,
XP_024302551.1,
XP_005249816.1,
XP_011513710.1
|
| Others |
UniRef100:
UniRef100_E9PCR7,
UniRef100_Q02218,
UniRef100_B4E3E9,
UniRef100_A0A140VJQ5
UniRef90:
UniRef90_Q60597-3,
UniRef90_B4E3E9,
UniRef90_Q02218,
UniRef90_A0A140VJQ5
UniRef50:
UniRef50_Q9ULD0-2,
UniRef50_Q02218,
UniRef50_A0A140VJQ5
UniGene:
Hs.488181
CCDS:
CCDS55107.1,
CCDS34627.1,
CCDS47580.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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