| Type | Description |
|---|---|
| Definition | ORF73 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 12:07:00 | LANA upregulates let-7a and its primary transcripts in parallel with its reduction of RBPJ expression. | 30856484 |
| 2017-12-16 11:00:00 | research shows that intact LANA traffics to the cytoplasm of cells undergoing permissive lytic infections and latently infected cells in which the virus is induced to replicate. This suggests that LANA plays important roles in the cytoplasm and nuclear compartments of the cell during different stages of the life Kaposi's sarcoma-associated herpesvirus cycle. | 28978712 |
| 2017-09-30 13:46:00 | The findings highlight a second point at which cytoplasmic LANA interferes with the innate immune response, as well as the importance of the recently discovered role of cytoplasmic MRN complex members as innate sensors of cytoplasmic DNA for the control of KSHV replication. | 28430817 |
| 2017-09-30 10:42:00 | the Kaposi Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen (LANA) is capable of supporting Murine Gammaherpesvirus 68 latency in a mouse model of chronic infection but also functions to repress viral replication. | 28747501 |
| 2017-06-24 11:35:00 | KSHV LANA recruits host PRCs onto the lytic promoters to suppress lytic gene expression following de novo infection. | 27606464 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LANA1_HHV8P
UniprotKB:
Q9QR71
UniParc:
UPI00000EBD78
EMBL:
AF148805
KO:
vg:4961527
|
| Nucleutide sequences |
EMBL-CDS:
AAD46501.1
Gene_ORFName:
ORF73
|
| Protein sequencees |
RefSeq:
YP_001129431.1
|
| Others |
UniRef100:
UniRef100_Q9QR71
UniRef90:
UniRef90_Q9QR71
UniRef50:
UniRef50_Q9QR71
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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