| Type | Description |
|---|---|
| Definition | ORF57 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:29:00 | we report the important roles of GW182 and DDX6, but not Dicer, Ago2 and DCP1A, in PB formation, and that Kaposi's sarcoma-associated herpesvirus (KSHV) lytic infection reduces PB formation through several specific interactions with viral RNA-binding protein ORF57 | 31400113 |
| 2019-11-02 12:01:00 | In both ORF57 and ICP27 the interaction sites for ALYREF and UIF partially overlap, suggestive of mutually exclusive binding. The data provide a map of the binding sites responsible for promoting herpes virus mRNA export, enabling future studies to accurately probe these interactions and reveal the functional consequences for UIF and ALYREF redundancy | 30301920 |
| 2019-01-26 11:26:00 | First structure of KSHV ORF57-CTD and new insights into the understanding of ORF57 protein dimerization and stability, which would shed light on the potential design of novel therapeutics against KSHV infection and related diseases. | 30096191 |
| 2017-11-25 12:38:00 | data provide the first evidence that KSHV ORF57 plays a role in modulating PKR/eIF2alpha/SG axis and enhances virus production during virus lytic infection. | 29084250 |
| 2017-05-13 22:31:00 | Herein, the authors extend their previous research and provide evidence that ORF57 of human herpesvirus-8 interacts with CHTOP and CIP29, in contrast to POLDIP3. | 27189710 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ICP27_HHV8P,
D0UZS0_HHV8
UniprotKB:
Q2HR75,
D0UZS0
UniParc:
UPI000004735C
EMBL:
MT510659,
KF588566,
MK143395,
MK876737,
MK876731,
MK876738,
MN419225,
MN419223,
MT510664,
MT510662,
MT510656,
MT510663,
KT271461,
MN419220,
JX228174,
HQ404500,
MK876733,
MK733609,
AF148805,
MK733608,
U93872,
MT510670,
MT510657,
MN419224,
MN419226,
MK733606,
MN419221,
MN419219,
MN419222,
MT510661,
MK733607,
MT510658,
MT510660,
MT510665,
MN752405,
GQ994935,
KT271463
KO:
vg:4961525
|
| Nucleutide sequences |
EMBL-CDS:
AAB62615.1,
ABD28908.1,
QKE51172.1,
AFQ99187.1,
QFU18853.1,
QKE51694.1,
QLF96718.1,
QKE51346.1,
QLF96971.1,
AKE33094.1,
QLI56344.1,
QLI55187.1,
ALH44915.1,
QLI55454.1,
QLF96634.1,
QLF96886.1,
ADQ57938.1,
QLI55543.1,
QAX88123.1,
QFU18766.1,
QLI55810.1,
QLF97056.1,
ALH45091.1,
QKE51781.1,
QLI55721.1,
QGX86291.1,
QLI55365.1,
QLF97141.1,
QFU18680.1,
QFU18594.1,
QLF96802.1,
QLI55098.1,
QLI55276.1,
QLF96550.1,
ACY00456.1,
QLI55632.1,
QLI55899.1
Gene_ORFName:
ORF57,
HHV8GK18_gp61
|
| Protein sequencees |
RefSeq:
YP_001129410.1
|
| Others |
UniRef100:
UniRef100_Q2HR75
UniRef90:
UniRef90_Q2HR75
UniRef50:
UniRef50_Q2HR75
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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